0055567
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T-Cell Clonality Screening by PCR

T CELL-F
Example Reports
Detected
Not Detected

Ordering Recommendation

Aid in the diagnosis of T-cell lymphoproliferative disorders.

Methodology

Capillary Electrophoresis/Polymerase Chain Reaction (PCR)

Performed

Varies

Reported

5-9 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) whole blood or bone marrow; tissue; formalin-fixed tissue.

Specimen Preparation

Whole Blood: Do not freeze. Transport 5 mL. (Min: 1 mL)
Bone Marrow: Do not freeze. Transport 3 mL. (Min: 1 mL)
Fresh Tissue: Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue
FFPE Tumor Tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Tissue block will be returned after testing. Transport tissue block or four 10-micron shavings in a tissue transport kit (ARUP Supply #47808) available online through eSupply using ARUP Connect or contact ARUP Client Services at 800-522-2787.

Storage/Transport Temperature

Whole Blood, Bone Marrow: Refrigerated.
Fresh Tissue: Frozen on dry ice.
FFPE Tumor Tissue: Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.

Unacceptable Conditions

Whole Blood, Bone Marrow: Plasma, serum. Specimens collected in anticoagulants other than EDTA or sodium heparin. Clotted or grossly hemolyzed specimens.
Tissue: Specimens fixed/processed in alternative fixatives, heavy metal fixatives (B-4 or B-5), or tissue sections on slides. Decalcified specimens.

Remarks

If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.

Stability

Whole Blood or Bone Marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE Tumor Tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
08/21/2023
X
X
11/14/2022
X
X
08/15/2022
X
N/A

CPT Codes

81342

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Components

Component Test Code* Component Chart Name LOINC
0055567 T-Cell Clonality by PCR 21753-9
2006285 T-Cell Clonality Source 66746-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • T Cell Gamma
  • T Cell Gene Rearrangement
  • T-cell receptor gamma rearrangement
  • T-Cell Receptor Gene Rearrangement
  • TCRG
T-Cell Clonality Screening by PCR