Ordering Recommendation
Aid in the diagnosis of T-cell lymphoproliferative disorders.
Mnemonic
Methodology
Capillary Electrophoresis
Performed
Varies
Reported
5-9 days
New York DOH Approval Status
Specimen Required
Lavender (EDTA) or green (sodium heparin) whole blood or bone marrow; tissue; formalin-fixed tissue.
Whole Blood: Do not freeze. Transport 5 mL. (Min: 1 mL)
Bone marrow: Do not freeze. Transport 3 mL. (Min: 1 mL)
Fresh Tissue: Freeze immediately. Transport 100 mg or 0.5-2.0 cm3 tissue
FFPE Tumor Tissue: Formalin fix (10 percent neutral buffered formalin) and paraffin embed tissue. Protect from excessive heat. Tissue block will be returned after testing. Transport tissue block or four 10-micron shavings in a tissue transport kit (ARUP Supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787.
Whole Blood, Bone Marrow: Refrigerated.
Fresh Tissue: Frozen on dry ice.
FFPE Tumor Tissue: Room temperature. Also acceptable: Refrigerated. Ship in cooled container during summer months.
Whole Blood, Bone Marrow: Plasma, serum. Specimens collected in anticoagulants other than EDTA or sodium heparin. Clotted or grossly hemolyzed specimens.
Tissue: Specimens fixed/processed in alternative fixatives, heavy metal fixatives (B-4 or B-5), or tissue sections on slides. Decalcified specimens.
If multiple specimens (blocks or slides) are sent to ARUP, they must be accompanied by one of the following: an order comment indicating that the ARUP pathologist should choose the specimen most appropriate for testing (e.g., "Choose best block"), or individual orders for each sample submitted. A Pathologist Block Selection Fee (ARUP test code 3002076) will be added to orders that utilize the first option. If multiple specimens are sent to ARUP without a request for pathologist block/slide selection or individual orders, they will be held until clarification is provided.
Whole Blood or Bone Marrow: Ambient: 24 hours; Refrigerated: 5 days; Frozen: Unacceptable
Fresh Tissue: Ambient: Unacceptable; Refrigerated: 2 hours; Frozen: 1 year
FFPE Tumor Tissue: Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Reference Interval
Interpretive Data
Refer to report.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Laboratory Developed Test (LDT)
Note
Hotline History
Hotline History
CPT Codes
81342
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0055567 | T-Cell Clonality by PCR | 21753-9 |
2006285 | T-Cell Clonality Source | 66746-9 |
Aliases
- T Cell Gamma
- T Cell Gene Rearrangement
- T-cell receptor gamma rearrangement
- T-Cell Receptor Gene Rearrangement
- TCRG