Ordering Recommendation
Mnemonic
SEMOLDPRO
Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum separator tube. Multiple specimen tubes should be avoided.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1.15 mL serum to an ARUP Standard Transport Tube. (Min: 0.6 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

Allergens included: Alternaria alternata (tenuis), Aspergillus fumigatus, Aureobasidium pullulans, Curvularia lunata, Epicoccum pupurascens, Fusarium moniliforme, Helminthosporium halodes (satiorium), Hormodendrum hordei (Cladosporium), Penicillium notatum, Rhizopus nigricans.

Effective 02/18/2014

Reporting Range
(reported in kU/L)
Probability of IgE Mediated
Clinical Reaction
Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86003 x10

Components
Component Test Code* Component Chart Name LOINC
0055001 Allergen, Fungi/Mold, A. alternata IgE 6020-2
0055038 Allergen, Fungi/Mold, Hormodendrum IgE 6075-6
0055041 Allergen, Interp, Immunocap Score IgE 33536-4
0055061 Allergen, Fungi/Mold, A. fumigatus IgE 6025-1
0055080 Allergen, Fungi/Mold, P. notatum IgE 6212-5
0055376 Allergen, Fungi/Mold, F. moniliforme IgE 6121-8
0055377 Allergen, Fungi/Mold, C. lunata IgE 7271-0
0055383 Allergen, Fungi/Mold, A. pullulans IgE 6029-3
0099541 Allergen, Fungi/Mold, Helminthospor. IgE 6138-2
0099555 Allergen, Fungi/Mold, R. nigricans IgE 6229-9
0099599 Allergen, Fungi/Mold, Epicoccum IgE 6111-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Allergens, Mold Profile, Southeast Comprehensive