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Allergens, Inhalants, Comprehensive Profile IgE
Ordering Recommendation
New York DOH Approval Status
Specimen Required
Multiple patient encounters should be avoided.
Serum separator tube. Multiple specimen tubes should be avoided.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 3.85 mL serum to an ARUP Standard Transport Tube. (Min: 1.68 mL)
Refrigerated.
Hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Methodology
Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay
Performed
Sun-Sat
Reported
1-3 days
Reference Interval
| Test Number |
Components |
Reference Interval |
||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Immunoglobulin E |
|
|||||||||||||||||||||||
| Allergen, Fungi/Mold, A. alternata IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Animal, Cat Dander IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Mountain Cedar Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Cottonwood Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Grass, June/Kentucky Blue IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Mugwort IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Russian Thistle IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Grass, Perennial Rye IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Grass, Timothy Grass IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Fungi/Mold, Hormodendrum IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Elm Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Animal, Cow Hair/Dander IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Oak Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Grass, Johnson Grass IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, English Plantain IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Animal, Horse Hair/Dander IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Fungi/Mold, A. fumigatus IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Mites, D. pteronyssinus IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Mites, D. farinae IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Grass, Bermuda Grass IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Fungi/Mold, P. notatum IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Common/Short Ragweed IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, House Dust Greer IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Mesquite Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Tree, Olive Tree IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Weed, Lambs Quarters IgE | Less than or equal to 0.34 kU/L | |||||||||||||||||||||||
| Allergen, Animal, Dog Dander IgE | Less than or equal to 0.34 kU/L |
Interpretive Data
Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.
| Reporting Range (reported in kU/L) | Probability of IgE Mediated Clinical Reaction | Class Scoring |
|---|---|---|
| Less than 0.10 | No significant level detected | 0 |
| 0.10 - 0.34 | Clinical relevance undetermined | 0/1 |
| 0.35 - 0.70 | Low | 1 |
| 0.71 - 3.50 | Moderate | 2 |
| 3.51 - 17.50 | High | 3 |
| 17.51 - 50.00 | Very high | 4 |
| 50.01 - 100.00 | Very high | 5 |
| Greater than 100.00 | Very high | 6 |
FDA
Note
Allergens included: Alternaria alternata (tenuis), Aspergillus fumigatus, Bermuda Grass, Cat Epithelium & Dander, Common/Short Ragweed, Cottonwood Tree, Cow Hair & Dander, D. farinae (Mites), D. pteronyssinus (Mites), Dog Dander, Elm Tree, English Plantain, Hormodendrum (Cladosporium), Horse Hair & Dander, House Dust Greer, IgE, Serum Total, Johnson Grass, June Grass/Kentucky Bluegrass, Lamb's Quarters, Mesquite Tree, Mountain Cedar (Juniper) Tree, Mugwort, Oak Tree, Olive Tree, Penicillium notatum, Perennial Rye Grass, Russian Thistle, and Timothy Grass.
Hotline History
CPT Codes
86003 x27; 82785
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050345 | Immunoglobulin E | 19113-0 |
| 0055001 | Allergen, Fungi/Mold, A. alternata IgE | 6020-2 |
| 0055006 | Allergen, Animal, Cat Dander IgE | 6833-8 |
| 0055007 | Allergen, Tree, Mountain Cedar Tree IgE | 6178-8 |
| 0055010 | Allergen, Tree, Cottonwood Tree IgE | 6090-5 |
| 0055017 | Allergen, Grass, June/Kentucky Blue IgE | 6153-1 |
| 0055021 | Allergen, Weed, Mugwort IgE | 6183-8 |
| 0055027 | Allergen, Weed, Russian Thistle IgE | 6234-9 |
| 0055028 | Allergen, Grass, Perennial Rye IgE | 7369-2 |
| 0055032 | Allergen, Grass, Timothy Grass IgE | 6265-3 |
| 0055038 | Allergen, Fungi/Mold, Hormodendrum IgE | 6075-6 |
| 0055041 | Allergen, Interp, Immunocap Score IgE | 48767-8 |
| 0055042 | Allergen, Tree, Elm Tree IgE | 6109-3 |
| 0055044 | Allergen, Animal, Cow Hair/Dander IgE | 6091-3 |
| 0055045 | Allergen, Tree, Oak Tree IgE | 6189-5 |
| 0055047 | Allergen, Grass, Johnson Grass IgE | 6152-3 |
| 0055049 | Allergen, Weed, English Plantain IgE | 6110-1 |
| 0055059 | Allergen, Animal, Horse Hair/Dander IgE | 6143-2 |
| 0055061 | Allergen, Fungi/Mold, A. fumigatus IgE | 6025-1 |
| 0055063 | Allergen, Mites, D. pteronyssinus IgE | 6096-2 |
| 0055064 | Allergen, Mites, D. farinae IgE | 6095-4 |
| 0055070 | Allergen, Grass, Bermuda Grass IgE | 6041-8 |
| 0055080 | Allergen, Fungi/Mold, P. notatum IgE | 6212-5 |
| 0055085 | Allergen, Weed, Common/Short Ragweed IgE | 6085-5 |
| 0055091 | Allergen, House Dust Greer IgE | 9828-5 |
| 0055140 | Allergen, Tree, Mesquite Tree IgE | 6173-9 |
| 0055155 | Allergen, Tree, Olive Tree IgE | 6192-9 |
| 0055160 | Allergen, Weed, Lambs Quarters IgE | 6156-4 |
| 0099568 | Allergen, Animal, Dog Dander IgE | 6098-8 |
