Allergens, Inhalants, Comprehensive Profile IgE

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Ordering Recommendation

Mnemonic

AZ TOT PAN

Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum separator tube. Multiple specimen tubes should be avoided.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3.85 mL serum to an ARUP Standard Transport Tube. (Min: 1.68 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

Test Number
 Components
 Reference Interval
  Immunoglobulin E
Age Reference Interval (kU/L)
0-5 months 13 or less
6-12 months 34 or less
1-2 years 97 or less
3 years 199 or less
4-6 years 307 or less
7-8 years 403 or less
9-12 years 696 or less
13-15 years 629 or less
16-17 years 537 or less
18 years and older 214 or less

  Allergen, Fungi/Mold, A. alternata IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Cat Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Mountain Cedar Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Cottonwood Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, June/Kentucky Blue IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Mugwort IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Russian Thistle IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Perennial Rye IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Timothy Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, Hormodendrum IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Elm Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Cow Hair/Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Oak Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Johnson Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, English Plantain IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Horse Hair/Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, A. fumigatus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. pteronyssinus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. farinae IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Bermuda Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, P. notatum IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Common/Short Ragweed IgE Less than or equal to 0.34 kU/L
  Allergen, House Dust Greer IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Mesquite Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Olive Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Lambs Quarters IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Dog Dander IgE Less than or equal to 0.34 kU/L

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.


Reporting Range (reported in kU/L) Probability of IgE Mediated Clinical Reaction Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Compliance Category

FDA

Note

Allergens included: Alternaria alternata (tenuis), Aspergillus fumigatus, Bermuda Grass, Cat Epithelium & Dander, Common/Short Ragweed, Cottonwood Tree, Cow Hair & Dander, D. farinae (Mites), D. pteronyssinus (Mites), Dog Dander, Elm Tree, English Plantain, Hormodendrum (Cladosporium), Horse Hair & Dander, House Dust Greer, IgE, Serum Total, Johnson Grass, June Grass/Kentucky Bluegrass, Lamb's Quarters, Mesquite Tree, Mountain Cedar (Juniper) Tree, Mugwort, Oak Tree, Olive Tree, Penicillium notatum, Perennial Rye Grass, Russian Thistle, and Timothy Grass.

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
02/15/2022
X
N/A

CPT Codes

86003 x27; 82785

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Components

Component Test Code* Component Chart Name LOINC
0050345 Immunoglobulin E 19113-0
0055001 Allergen, Fungi/Mold, A. alternata IgE 6020-2
0055006 Allergen, Animal, Cat Dander IgE 6833-8
0055007 Allergen, Tree, Mountain Cedar Tree IgE 6178-8
0055010 Allergen, Tree, Cottonwood Tree IgE 6090-5
0055017 Allergen, Grass, June/Kentucky Blue IgE 6153-1
0055021 Allergen, Weed, Mugwort IgE 6183-8
0055027 Allergen, Weed, Russian Thistle IgE 6234-9
0055028 Allergen, Grass, Perennial Rye IgE 7369-2
0055032 Allergen, Grass, Timothy Grass IgE 6265-3
0055038 Allergen, Fungi/Mold, Hormodendrum IgE 6075-6
0055041 Allergen, Interp, Immunocap Score IgE 33536-4
0055042 Allergen, Tree, Elm Tree IgE 6109-3
0055044 Allergen, Animal, Cow Hair/Dander IgE 6091-3
0055045 Allergen, Tree, Oak Tree IgE 6189-5
0055047 Allergen, Grass, Johnson Grass IgE 6152-3
0055049 Allergen, Weed, English Plantain IgE 6110-1
0055059 Allergen, Animal, Horse Hair/Dander IgE 6143-2
0055061 Allergen, Fungi/Mold, A. fumigatus IgE 6025-1
0055063 Allergen, Mites, D. pteronyssinus IgE 6096-2
0055064 Allergen, Mites, D. farinae IgE 6095-4
0055070 Allergen, Grass, Bermuda Grass IgE 6041-8
0055080 Allergen, Fungi/Mold, P. notatum IgE 6212-5
0055085 Allergen, Weed, Common/Short Ragweed IgE 6085-5
0055091 Allergen, House Dust Greer IgE 9828-5
0055140 Allergen, Tree, Mesquite Tree IgE 6173-9
0055155 Allergen, Tree, Olive Tree IgE 6192-9
0055160 Allergen, Weed, Lambs Quarters IgE 6156-4
0099568 Allergen, Animal, Dog Dander IgE 6098-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Allergens, Inhalants, Comprehensive Profile IgE