Ordering Recommendation

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum separator tube. Multiple specimen tubes should be avoided.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3.85 mL serum to an ARUP Standard Transport Tube. (Min: 1.68 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Test Number
Components
Reference Interval
  Immunoglobulin E
Age Reference Interval (kU/L)
0-5 months 13 or less
6-12 months 34 or less
1-2 years 97 or less
3 years 199 or less
4-6 years 307 or less
7-8 years 403 or less
9-12 years 696 or less
13-15 years 629 or less
16-17 years 537 or less
18 years and older 214 or less

  Allergen, Fungi/Mold, A. alternata IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Cat Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Mountain Cedar Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Cottonwood Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, June/Kentucky Blue IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Mugwort IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Russian Thistle IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Perennial Rye IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Timothy Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, Hormodendrum IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Elm Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Cow Hair/Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Oak Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Johnson Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, English Plantain IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Horse Hair/Dander IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, A. fumigatus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. pteronyssinus IgE Less than or equal to 0.34 kU/L
  Allergen, Mites, D. farinae IgE Less than or equal to 0.34 kU/L
  Allergen, Grass, Bermuda Grass IgE Less than or equal to 0.34 kU/L
  Allergen, Fungi/Mold, P. notatum IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Common/Short Ragweed IgE Less than or equal to 0.34 kU/L
  Allergen, House Dust Greer IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Mesquite Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Tree, Olive Tree IgE Less than or equal to 0.34 kU/L
  Allergen, Weed, Lambs Quarters IgE Less than or equal to 0.34 kU/L
  Allergen, Animal, Dog Dander IgE Less than or equal to 0.34 kU/L

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.


Reporting Range (reported in kU/L) Probability of IgE Mediated Clinical Reaction Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Compliance Category

FDA

Note

Allergens included: Alternaria alternata (tenuis), Aspergillus fumigatus, Bermuda Grass, Cat Epithelium & Dander, Common/Short Ragweed, Cottonwood Tree, Cow Hair & Dander, D. farinae (Mites), D. pteronyssinus (Mites), Dog Dander, Elm Tree, English Plantain, Hormodendrum (Cladosporium), Horse Hair & Dander, House Dust Greer, IgE, Serum Total, Johnson Grass, June Grass/Kentucky Bluegrass, Lamb's Quarters, Mesquite Tree, Mountain Cedar (Juniper) Tree, Mugwort, Oak Tree, Olive Tree, Penicillium notatum, Perennial Rye Grass, Russian Thistle, and Timothy Grass.

Hotline History

N/A

CPT Codes

86003 x27; 82785

Components

* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

Allergens, Inhalants, Comprehensive Profile IgE