Ordering Recommendation

Detect the presence of CSF IgG antibodies to T. solium if clinical suspicion of cysticercosis exists.

Mnemonic
CYST CSF
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sat

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Serum. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
0.8 IV or less Negative - No significant level of cysticercosis IgG antibody detected.
0.9 - 1.1 IV Equivocal - Questionable presence of cysticercosis IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.2 IV or greater Positive - IgG antibodies to cysticercosis detected, which may suggest current or past infection.

Interpretive Data

Diagnosis of central nervous system infections can be accomplished by demonstrating the presence of intrathecally-produced specific antibody. Interpretation of results may be complicated by low antibody levels found in CSF, passive transfer of antibody from blood, and contamination via bloody taps.
A negative result does not rule out infection. Repeat testing after 4 weeks if clinical suspicion is high.
Cross-reaction with antibodies against Echinococcus ssp. have been reported. 

Compliance Category

Modified FDA

Note
Hotline History
N/A
CPT Codes

86682

Components
Component Test Code* Component Chart Name LOINC
0055285 Cysticercosis Ab, IgG by ELISA, CSF 35391-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cysticercosis AB, ELISA (CSF)
  • Neurocysticercosis
  • Taenia solium Antibody
  • Taenia solium Antibody CSF
  • Tapeworm IgG antibody CSF
Cysticercosis Antibody, IgG by ELISA (CSF)