Ordering Recommendation

Detect the presence of CSF IgG antibodies to T. solium if clinical suspicion of cysticercosis exists.

Mnemonic
CYST CSF
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sat

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Serum. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
0.8 IV or less Negative - No significant level of cysticercosis IgG antibody detected.
0.9 - 1.1 IV Equivocal - Questionable presence of cysticercosis IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.2 IV or greater Positive - IgG antibodies to cysticercosis detected, which may suggest current or past infection.

Interpretive Data

Diagnosis of central nervous system infections can be accomplished by demonstrating the presence of intrathecally-produced specific antibody. Interpretation of results may be complicated by low antibody levels found in CSF, passive transfer of antibody from blood, and contamination via bloody taps.
A negative result does not rule out infection. Repeat testing after 4 weeks if clinical suspicion is high.
Cross-reaction with antibodies against Echinococcus ssp. have been reported. 

Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.

Note
Hotline History
N/A
CPT Codes

86682

Components
Component Test Code* Component Chart Name LOINC
0055285 Cysticercosis Ab, IgG by ELISA, CSF 35391-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cysticercosis AB, ELISA (CSF)
  • Neurocysticercosis
  • Taenia solium Antibody
  • Taenia solium Antibody CSF
  • Tapeworm IgG antibody CSF
Cysticercosis Antibody, IgG by ELISA (CSF)