Ordering Recommendation

Detect presence of IgG antibodies to T. solium in serum if clinical suspicion of cysticercosis exists.

Mnemonic
CYST SER
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sat

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

CSF. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Effective April 3, 2019

0.8 IV or less Negative - No significant level of cysticercosis IgG antibody detected.
0.9 - 1.1 IV Equivocal - Questionable presence of cysticercosis IgG antibody detected. Repeat testing in 10-14 days may be helpful.
1.2 IV or greater Positive - IgG antibodies to cysticercosis detected, which may suggest current or past infection.

Interpretive Data

Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.

Patients with collagen vascular diseases, hepatic cirrhosis, schistosomiasis, and other parasitic infections can produce false-positive results. There is a strong cross-reaction between cysticercosis and echinococcosis positive sera. Confirmation of positive ELISA results by the cysticercosis antibody, IgG by Western blot is recommended.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86682

Components
Component Test Code* Component Chart Name LOINC
0055284 Cysticercosis Ab, IgG by ELISA 25389-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Cysticercosis AB, ELISA
  • Neurocysticercosis
  • Taenia solium Antibody
  • Taenia solium IgG Antibody
  • Tapeworm IgG antibody
Cysticercosis Antibody, IgG by ELISA