Ordering Recommendation

For CSF specimens, Treponema pallidum (VDRL), Cerebrospinal Fluid with Reflex to Titer is preferred. May aid in the workup of neurosyphilis.

Mnemonic
FTA CSF G
Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 1 mL CSF to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Serum. Contaminated, heat-inactivated, or hemolyzed specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 5 days; Frozen: 1 year

Reference Interval

Nonreactive

Interpretive Data

The significance of a reactive result in the FTA-ABS CSF test is unknown. The CSF from persons treated in the secondary or latent stage of syphilis and without signs of neurosyphilis may be reactive. A nonreactive result in the FTA-ABS CSF test suggests the absence of neurosyphilis.

Treponema pallidum (VDRL), Cerebrospinal Fluid with Reflex to Titer (0050206) is the recommended test for CSF specimens.  If suspicion of neurosyphilis remains after VDRL testing, testing of the CSF with FTA-ABS may be considered.

Compliance Category

Modified FDA

Note
Hotline History
N/A
CPT Codes

86780

Components
Component Test Code* Component Chart Name LOINC
0055273 Fluorescent Treponema Antibody CSF 9826-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Fluorescent Treponemal Antibody
  • T pallidum IgG CSF by IFA
Treponema pallidum Antibody, IgG by IFA (CSF)