0055235
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Soluble Liver Antigen Antibody, IgG

SLA
Example Reports
Negative
Positive

Ordering Recommendation

Recommended for the evaluation of autoimmune liver disease or hepatitis of unknown etiology.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun, Tue, Thu

Reported

1-4 days

Reference Interval

0.0-20.0 U Negative
20.1-24.9 U Equivocal
Greater than or equal to 25.0 U Positive

Interpretive Data

The presence of SLA antibodies has almost 100% specificity for autoimmune hepatitis, although only 12-30% have these antibodies.  Thus, a negative SLA IgG test does not rule out autoimmune hepatitis.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

83516

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Components

Component Test Code* Component Chart Name LOINC
0055235 Soluble Liver Antigen Antibody, IgG 38420-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Anti-SLA-LP
  • Anti-SLA/LP
Soluble Liver Antigen Antibody, IgG