Ordering Recommendation
Recommended for the evaluation of autoimmune liver disease or hepatitis of unknown etiology.
Mnemonic
SLA
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun, Tue, Thu
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube.
Specimen Preparation
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Contaminated, heat-inactivated, hemolyzed, or lipemic specimens.
Remarks
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
0.0-20.0 U | Negative |
20.1-24.9 U | Equivocal |
Greater than or equal to 25.0 U | Positive |
Interpretive Data
The presence of SLA antibodies has almost 100% specificity for autoimmune hepatitis, although only 12-30% have these antibodies. Thus, a negative SLA IgG test does not rule out autoimmune hepatitis.
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
83516
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0055235 | Soluble Liver Antigen Antibody, IgG | 38420-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Anti-SLA-LP
- Anti-SLA/LP
Soluble Liver Antigen Antibody, IgG