Ordering Recommendation

Aid in evaluation and management of multiple myeloma and related plasma cell disorders. Indicated for the diagnosis of patients with oligosecretory or nonsecretory multiple myeloma and light chain amyloidosis.

Mnemonic
KAP/LAM F
Methodology

Quantitative Immunoturbidimetry

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma.

Remarks
Stability

After separation from cells: Ambient: Unacceptable; Refrigerated: 3 weeks; Frozen: 6 months

Reference Interval
Test Number
Components
Reference Interval
  Lambda Qnt Free Light Chains Effective February 18, 2020
5.71-26.30 mg/L
  Kappa Qnt Free Light Chains Effective February 18, 2020
3.30 - 19.40 mg/L
  Kappa/Lambda Free Light Chain Ratio 0.26-1.65

Interpretive Data

Undetected antigen excess is a rare event but cannot be excluded. Free light chain results should always be interpreted in conjunction with other clinical and laboratory findings.

No compliance statements are in use for this test.

Note

This assay is highly sensitive to increasing concentrations of monoclonal free kappa or free lambda light chains in the serum of patients with evolving or relapsing myelomas.

Hotline History
N/A
CPT Codes

83520 x2

Components
Component Test Code* Component Chart Name LOINC
0055168 Kappa Qnt Free Light Chains 36916-5
0055169 Lambda Qnt Free Light Chains 33944-0
0055179 Kappa/Lambda Free Light Chain Ratio 80517-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Kappa Qnt Free Light Chains
  • Kappa/Lambda Free Light Chain Ratio
  • Lambda Qnt Free Light Chains
Kappa/Lambda Quantitative Free Light Chains with Ratio, Serum