Ordering Recommendation
Mnemonic
COMP 29
Methodology

Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Performed

Sun-Sat

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Multiple patient encounters should be avoided.

Collect

Serum separator tube. Multiple specimen tubes should be avoided.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 3.05 mL serum to an ARUP Standard Transport Tube. (Min: 1.36 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Hemolyzed, icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

Allergens included: Alternaria alternata (tenuis), Bermuda Grass, Cat Epithelium & Dander, Corn, D. farinae (Mites), Dog Dander, Egg White, Eucalyptus Tree, Goldenrod, Hormodendrum (Cladosporium), House Dust Stier, June Grass/Kentucky Bluegrass, Kochia/Firebush, Box Elder/Maple Tree, Milk (Cow's) , Mugwort, Oak Tree, Orange, Peanut, Penicillium notatum, Perennial Rye Grass, Russian Thistle, Shrimp, Soybean, Sycamore Tree, Timothy Grass, Western Ragweed, Wheat, White Ash Tree.

Effective 02/18/2014

Reporting Range
(reported in kU/L)
Probability of IgE Mediated
Clinical Reaction
Class Scoring
Less than 0.10 No significant level detected 0
0.10 - 0.34 Clinical relevance undetermined 0/1
0.35 - 0.70 Low 1
0.71 - 3.50 Moderate 2
3.51 - 17.50 High 3
17.51 - 50.00 Very high 4
50.01 - 100.00 Very high 5
Greater than 100.00 Very high 6

Interpretive Data

Allergen results of 0.10-0.34 kU/L are intended for specialist use as the clinical relevance is undetermined. Even though increasing ranges are reflective of increasing concentrations of allergen-specific IgE, these concentrations may not correlate with the degree of clinical response or skin testing results when challenged with a specific allergen. The correlation of allergy laboratory results with clinical history and in vivo reactivity to specific allergens is essential. A negative test may not rule out clinical allergy or even anaphylaxis.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86003 x29

Components
Component Test Code* Component Chart Name LOINC
0055001 Allergen, Fungi/Mold, A. alternata IgE 6020-2
0055003 Allergen, Tree, Box Elder/Maple Tree IgE 7155-5
0055006 Allergen, Animal, Cat Dander IgE 6833-8
0055013 Allergen, Food, Egg White IgE 6106-9
0055017 Allergen, Grass, June/Kentucky Blue IgE 6153-1
0055018 Allergen, Weed, Kochia/Firebush IgE 6118-4
0055020 Allergen, Food, Milk (Cow) IgE 7258-7
0055021 Allergen, Weed, Mugwort IgE 6183-8
0055023 Allergen, Food, Orange IgE 6194-5
0055024 Allergen, Food, Peanut IgE 6206-7
0055027 Allergen, Weed, Russian Thistle IgE 6234-9
0055028 Allergen, Grass, Perennial Rye IgE 7369-2
0055030 Allergen, Food, Shrimp IgE 6246-3
0055031 Allergen, Food, Soybean IgE 6248-9
0055032 Allergen, Grass, Timothy Grass IgE 6265-3
0055034 Allergen, Food, Wheat IgE 6276-0
0055035 Allergen, Weed, Western Ragweed IgE 6275-2
0055038 Allergen, Fungi/Mold, Hormodendrum IgE 6075-6
0055041 Allergen, Interp, Immunocap Score IgE 33536-4
0055045 Allergen, Tree, Oak Tree IgE 6189-5
0055064 Allergen, Mites, D. farinae IgE 6095-4
0055070 Allergen, Grass, Bermuda Grass IgE 6041-8
0055073 Allergen, Tree, White Ash Tree IgE 6278-6
0055078 Allergen, Food, Corn IgE 6087-1
0055080 Allergen, Fungi/Mold, P. notatum IgE 6212-5
0055090 Allergen, Tree, Sycamore Tree IgE 15285-0
0055092 Allergen, House Dust Stier IgE 7425-2
0055098 Allergen, Tree, Eucalyptus Tree IgE 6113-5
0098471 Allergen, Weed, Goldenrod IgE 6128-3
0099568 Allergen, Animal, Dog Dander IgE 6098-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Allergens, Inhalants/Foods, Comprehensive Profile 2