Generally not recommended for the diagnosis of acute disease/encephalitis. May aid in diagnosing varicella-zoster virus vasculopathy.
Semi-Quantitative Chemiluminescent Immunoassay
Sun - Sat
Within 24 hours
Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Refrigerated. Also acceptable: Frozen.
Contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.
Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year
Effective February 18, 2020
|134.9 IV or less||Negative - No significant level of IgG antibody to varicella-zoster virus detected.|
|135.0-164.9 IV||Equivocal - Repeat testing in 10-14 days may be helpful.|
|165.0 IV or greater||Positive - IgG antibody to varicella-zoster virus detected, which may indicate a current or past varicella-zoster infection.|
The detection of antibodies to varicella-zoster in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.
Compliance Statement B: For laboratory developed tests not using a RUO kit, and for FDA approved, cleared or 510(k) exempt assays with alterations. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, FDA clearance or approval is not currently required for clinical use. The results are not intended to be used as the sole means for clinical diagnosis or patient management decisions.
|Component Test Code*||Component Chart Name||LOINC|
|0054444||VZV Antibody IgG CSF||58755-0|
- CSF VZV
- Herpes Zoster Antibodies CSF
- Varicella-Zoster Antibody CSF
- Varicella-zoster IgG CSF
- VZ AB IgG CSF
- VZ Ab, CSF