Ordering Recommendation

Aid in the diagnosis of measles encephalitis. False-positive results will occur due to low incidence of measles in the U.S.

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation


Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.2 mL)
New York State Clients: 1 mL (Min: 0.075 mL)

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.
New York State Clients: Refrigerated

Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.


Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year
New York State Clients: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 month


Semi-Quantitative Enzyme-Linked Immunosorbent Assay




1-5 days

Reference Interval

0.79 AU or less Negative - No significant level of IgM antibodies to measles (rubeola) virus detected.
0.80-1.20 AU Equivocal - Repeat testing in 10-14 days may be helpful.
1.21 AU or greater Positive - IgM antibodies to measles (rubeola) virus detected. Suggestive of current or recent infection or immunization.  However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

Interpretive Data

The detection of antibodies to rubeola in CSF may indicate central nervous system infection.  However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0054441 Measles, Rubeola, Antibody IgM CSF 13283-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • English Measles
  • measles IgM CSF
  • MMR
  • Rubeola IgM CSF
Measles (Rubeola) Antibody, IgM, CSF