Ordering Recommendation

Not a recommended test. False-positive results will occur due to low incidence of measles in the U.S.

Mnemonic
MEASLGCSF
Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
Specimens from New York clients will be sent out to a New York DOH approved laboratory, if possible.
Specimen Required
Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.

Remarks
Stability

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year.

Reference Interval

Effective September 3, 2019

13.4 AU/mL or less Negative - No significant level of IgG antibody to measles (rubeola) virus detected.
13.5-16.4 AU/mL Equivocal - Repeat testing in 10-14 days may be helpful.
16.5 AU/mL or greater Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past measles (rubeola) infection.

Interpretive Data

The detection of antibodies to rubeola in CSF may indicate central nervous system infection.  However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

Compliance Category

Modified FDA

Note
Hotline History
N/A
CPT Codes

86765

Components
Component Test Code* Component Chart Name LOINC
0054440 Measles, Rubeola, Antibody IgG CSF 9566-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CSF IgG Rubeola
  • Rubeola Ab, IgG, CSF
  • Rubeola Abs CSF
  • Rubeola Antibodies, IgG
Measles (Rubeola) Antibody, IgG, CSF