Ordering Recommendation

Not a recommended test. False-positive results will occur due to low incidence of measles in the U.S.

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation


Specimen Preparation

Transfer 0.5 mL CSF to an ARUP Standard Transport Tube. (Min: 0.3 mL)
New York State Clients: 1 mL (Min: 0.075 mL)

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.
New York State Clients: Refrigerated

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.


Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year.
New York State Clients: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 month


Semi-Quantitative Chemiluminescent Immunoassay




Within 24 hours

Reference Interval

Effective September 3, 2019

13.4 AU/mL or less Negative - No significant level of IgG antibody to measles (rubeola) virus detected.
13.5-16.4 AU/mL Equivocal - Repeat testing in 10-14 days may be helpful.
16.5 AU/mL or greater Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past measles (rubeola) infection.

Interpretive Data

The detection of antibodies to rubeola in CSF may indicate central nervous system infection.  However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Modified FDA


Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0054440 Measles, Rubeola, Antibody IgG CSF 9566-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • CSF IgG Rubeola
  • Rubeola Ab, IgG, CSF
  • Rubeola Abs CSF
  • Rubeola Antibodies, IgG
Measles (Rubeola) Antibody, IgG, CSF