Ordering Recommendation

Not a recommended test. False-positive results will occur due to low incidence of measles in the U.S.

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 0.5 mL CSF to an ARUP standard transport tube. (Min: 0.3 mL)
New York State Clients: 1 mL (Min: 0.075 mL)

Storage/Transport Temperature

Refrigerated. Also acceptable: Frozen.
New York State Clients: Refrigerated

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or xanthochromic specimens.

Remarks
Stability

Ambient: 8 hours; Refrigerated: 2 weeks; Frozen: 1 year.
New York State Clients: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 1 month

Methodology

Semi-Quantitative Chemiluminescent Immunoassay (CLIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
Components
Reference Interval
  Measles, Rubeola, Antibody IgG CSF Less than or equal to 13.4 AU/mL

Interpretive Data

  The detection of antibodies to rubeola in CSF may indicate central nervous system infection. However, consideration must be given to possible contamination by blood or transfer of serum antibodies across the blood-brain barrier.


13.4 AU/mL or less Negative - No significant level of IgG antibody to measles (rubeola) virus detected.
13.5-16.4 AU/mL Equivocal - Repeat testing in 10-14 days may be helpful.
16.5 AU/mL or greater Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past measles (rubeola) infection.

Compliance Category

Modified FDA

Note

Hotline History

N/A

CPT Codes

86765

Components

Component Test Code* Component Chart Name LOINC
0054440 Measles, Rubeola, Antibody IgG CSF 9566-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • CSF IgG Rubeola
  • Rubeola Ab, IgG, CSF
  • Rubeola Abs CSF
  • Rubeola Antibodies, IgG
Measles (Rubeola) Antibody, IgG, CSF