Cytomegalovirus by Quantitative PCR

0051813
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Example Reports
Detected
Not Detected
Ordering Recommendation

Detect and quantify cytomegalovirus (CMV).

Mnemonic
CMV QNT
Methodology

Quantitative Polymerase Chain Reaction

Performed

Sun-Sat

Reported

2-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA) or pink (K2EDTA), or Bronchoalveolar lavage (BAL).

Specimen Preparation

Separate plasma from cells. Transfer 1 mL plasma, or whole blood, or BAL to a sterile container. (Min: 0.5 mL).

Storage/Transport Temperature

Whole blood: Refrigerated. All others: Frozen.

Unacceptable Conditions

Heparinized specimens.

Remarks

Specimen source required.

Stability

Plasma: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year 
Whole blood: Ambient: 7 days; Refrigerated: 7 days; Frozen: 7 days
BAL: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 3 months

Reference Interval

Not detected

Interpretive Data

The quantitative range of this test is 2.6- 6.6 log copies/mL (390-3,900,000 copies/mL) or 2.4- 6.4 log IU/mL (227- 2,270,000 IU/mL). One IU/mL of CMV DNA is approximately 1.72 copies/mL.

A negative result (less than 2.6 log copies/mL [less than 390 copies/mL] OR less than 2.4 log IU/mL [less than 227 IU/mL]) does not rule out the presence of PCR inhibitors in the patient specimen or CMV DNA concentrations below the level of detection of the test. Inhibition may also lead to underestimation of viral quantitation.

Compliance Category

Analyte Specific Reagent (ASR)

Note

The limit of quantification for this DNA test is 2.6 log copies/mL (390 copies/mL) or 2.4 log IU/mL (227 IU/mL). If the test DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)" and "<2.4 log IU/mL (<227 IU/mL)."  If the test DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
09/08/2020
X
N/A
CPT Codes

87497

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Components
Component Test Code* Component Chart Name LOINC
0051814 Cytomegalovirus Quant by PCR, Interp 40444-2
0051815 Cytomegalovirus Quant by PCR, Log Cpy/mL 54206-8
2002316 Cytomegalovirus Quant by PCR, Cpy/mL 30247-1
2006534 Cytomegalovirus Quant by PCR, IU/mL 72493-0
2006535 Cytomegalovirus Quant by PCR, Log IU/mL 72494-8
2012051 Cytomegalovirus Quant by PCR, Source 31208-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • CMV Quant PCR
  • CMV quantitative
  • herpes
  • HHV-5
  • Human herpesvirus 5
  • Viral load monitoring
Cytomegalovirus by Quantitative PCR