Do not use to screen for celiac disease. May be used to estimate severity of intestinal villous atrophy in confirmed celiac disease.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Serum separator tube.
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Plasma. Contaminated, severely hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
|20.0 Units or less||Negative|
|20.1 - 24.9 Units||Equivocal|
|25.0 Units or greater||Positive|
The presence of IgA antibodies against F-Actin in patients having positive serologic markers for celiac disease, such as antiendomysial, anti-transglutaminase, and/or anti-gliadin peptide IgA, indicates the presence of intestinal villus atrophy. Positive results should be confirmed with biopsy.
|Component Test Code*||Component Chart Name||LOINC|
|0051725||F-Actin Antibody, IgA||63210-9|
- Actin Antibody
- Anti-Smooth Muscle Antibody
- F-Actin Antibody