Acceptable single screening test for celiac disease. Screen includes tTG antibodies IgA and IgG, and DGP antibodies IgA and IgG. Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgA (0097709) is the preferred test for screening patients with suspected celiac disease.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Mon, Wed, Fri
Serum separator tube.
Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Plasma or other body fluids. Contaminated, heat-inactivated, hemolyzed, icteric, or lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
|19 Units or less||Negative - No significant level of detectable IgA or IgG antibodies against human tissue transglutaminase or gliadin peptide.|
|20 Units or greater||Positive - Presence of IgA and/or IgA antibodies against human tissue transglutaminase and/or gliadin peptide; suggests possibility of certain gluten sensitive enteropathies such as celiac disease and dermatitis herpetiformis.|
This test is a combined antibody screen for tissue transglutaminase and deamidated gliadin-derived peptide antibodies, IgA and IgG.
|Component Test Code*||Component Chart Name||LOINC|
|0051691||Celiac Disease Dual Antigen Screen||63420-4|
- Celiac Sprue
- Combined tissue Transglutaminase (tTG) and deamidated (DGP) IgG and IgA
- combined tTG and DGP IgG and IGA