Ordering Recommendation
Confirmatory test for more common systemic autoimmune rheumatic diseases (ie, connective tissue diseases).
Mnemonic
CONN
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Semi-Quantitative Multiplex Bead Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube.
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma or other body fluids. Bacterially contaminated specimens.
Remarks
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month
Reference Interval
Effective May 18, 2015
Test Number |
Components |
Reference Interval |
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0050085 | Smith (ENA) Antibody, IgG |
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0050470 | Smith/RNP (ENA) Antibody, IgG |
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2012074 | SSA 52 and 60 (Ro) (ENA) Antibodies, IgG |
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0050692 | SSB (La) (ENA) Antibody, IgG |
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0099592 | Jo-1 Antibody, IgG |
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0099249 | Ribosomal P Protein Antibody |
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0050714 | Centromere Antibody, IgG |
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0050599 | Scleroderma (Scl-70) (ENA) Antibody, IgG |
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Interpretive Data
Refer to report.
Compliance Category
FDA
Note
Hotline History
Hotline History
Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
N/A
CPT Codes
86235 x7; 83516 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050085 | Smith (ENA) Antibody, IgG | 18323-6 |
0050470 | Smith/RNP (ENA) Ab, IgG | 33983-8 |
0050599 | Scleroderma (Scl-70) (ENA) Antibody, IgG | 47322-3 |
0050691 | SSA-52 (Ro52) (ENA) Antibody, IgG | 31625-7 |
0050692 | SSB (La) (ENA) Antibody, IgG | 29965-1 |
0050714 | Centromere Ab, IgG | 29966-9 |
0099249 | Ribosome P Antibody, IgG | 13636-6 |
0099592 | Jo-1 (Histidyl-tRNA Synthetase) Ab, IgG | 33571-1 |
2012055 | SSA-60 (Ro60) (ENA) Antibody, IgG | 53019-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Anti-ENA
- Anti-RNP
- Anti-Sm IgG
- Anti-SSA
- Anti-SSB
- Antibodies to Extractable Nuclear Antigens
- Autoantibodies to Scl 70 Antigen
- Ribonucleoprotein Autoantibodies
- Ro Ab
- Scl 70 Antibodies
- Scleroderma (Scl-70) (ENA) Antibody, IgG
- Scleroderma Antibodies
- Sm/RNP (ENA) Antibody, IgG
- Smith (ENA) Antibody, IgG
- Smith Antigen
- Smith Autoantibodies
- SmRNP Autoantibodies
- SSA (Ro) (ENA) Antibody, IgG
- SSA Ro
- SSB (La) (ENA) Antibody, IgG
- SSB LA
Connective Tissue Diseases Profile