Ordering Recommendation

Do not use for diagnosis of Epstein-Barr virus infectious mononucleosis. May aid in the detection and prognosis of nasopharyngeal carcinoma.




Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay




1-8 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Serum Separator Tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature


Unacceptable Conditions

Contaminated, heat-inactivated, or grossly hemolyzed specimens.


Label specimens plainly as "acute" or "convalescent."


After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month (Avoid repeated freeze/thaw cycles).

Reference Interval

Test Number
Reference Interval
0050235 Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG Effective February 19, 2013

17.9 U/mL or less: Not Detected
18.0-21.9 U/mL:  Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
0051626 Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgA Effective November 15, 2021
Reference Interval
8 U or less Not Detected
9-11 U Indeterminate - Repeat testing in 10-14 days may be helpful.
12 U or greater Detected

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

86665 x2


Component Test Code* Component Chart Name LOINC
0050235 EBV Antibody to Viral Capsid Antigen IgG 7885-7
0051626 EBV Antibody To Viral Capsid Antigen IgA 31369-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • EBV and VCA Ab
  • EBV Antibodies
  • EBV VCA- Ab
  • Infectious Mononucleosis
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG and IgA