Ordering Recommendation

Do not use for diagnosis of Epstein-Barr virus infectious mononucleosis. May aid in the detection and prognosis of nasopharyngeal carcinoma.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP standard transport tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, icteric, or grossly hemolyzed specimens.

Remarks

Label specimens plainly as "acute" or "convalescent."

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 month (Avoid repeated freeze/thaw cycles).

Methodology

Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay

Performed

Tue

Reported

1-8 days

Reference Interval

Test Number
Components
Reference Interval
  EBV Antibody to Viral Capsid Antigen IgG 21.9 U/mL or less
  EBV Antibody To Viral Capsid Antigen IgA 8 U or less

Interpretive Data




Component Interpretation
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG 17.9 U/mL or less: Not Detected
18.0-21.9 U/mL:  Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgA 8 U or less:  Not Detected
9-11 U: Indeterminate - Repeat testing in 10-14 days may be helpful.
12 U or greater: Detected

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

86665 x2

Components

Component Test Code* Component Chart Name LOINC
0050235 EBV Antibody to Viral Capsid Antigen IgG 7885-7
0051626 EBV Antibody To Viral Capsid Antigen IgA 31369-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • EBV and VCA Ab
  • EBV Antibodies
  • EBV VCA- Ab
  • Infectious Mononucleosis
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG and IgA