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Cytokine Panel, Monokines, Serum
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Ordering Recommendation
Primarily used for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.
Mnemonic
Methodology
Quantitative Multiplex Bead Assay
Performed
Sun-Sat
Reported
1-4 days
New York DOH Approval Status
Specimen Required
Serum separator tube, or plain red.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Ship in an ARUP Standard Transport Tube.
Refrigerated specimens. Contaminated or heat-inactivated specimens.
After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year
Reference Interval
| Test Number |
Components |
Reference Interval (pg/mL) |
|---|---|---|
| Interleukin 1 beta, Serum | 6.7 or less | |
| Interleukin 6, Serum | 2.0 or less | |
| Interleukin 8, Serum | 3.0 or less | |
| Tumor Necrosis Factor - alpha, Serum | 7.2 or less |
Interpretive Data
Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.
Laboratory Developed Test (LDT)
Note
Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day.
Hotline History
CPT Codes
83520 x3; 83529
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0051536 | Interleukin 1 beta, Serum | 13629-1 |
| 0051537 | Interleukin 6, Serum | 26881-3 |
| 0051538 | Interleukin 8, Serum | 33211-4 |
| 0051539 | Tumor Necrosis Factor - alpha, Serum | 3074-2 |
Aliases
- cytokine
- cytokines
- IL-1 Beta
- IL-6
- IL-8
- TNF Alpha
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