Ordering Recommendation

Primarily used for research and to support attempts to understand the pathogenesis of immune, infectious, allergic, or inflammatory disorders.

Mnemonic
CYT MON SE
Methodology

Quantitative Multiplex Bead Assay

Performed

Sun-Sat

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube, or plain red.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered. Ship in an ARUP Standard Transport Tube.

Unacceptable Conditions

Refrigerated specimens. Contaminated or heat-inactivated specimens.

Remarks
Stability

After separation from cells: Ambient: 30 minutes; Refrigerated: Unacceptable; Frozen: 1 year

Reference Interval
Test Number
Components
Reference Interval
0051536 Interleukin 1 beta, Serum Effective May 18, 2020
6.7 pg/mL or less
0051537 Interleukin 6, Serum Effective May 18, 2020
2.0 pg/mL or less
0051538 Interleukin 8, Serum Effective May 18, 2020
3.0 pg/mL or less
0051539 Tumor Necrosis Factor - alpha, Serum Effective May 18, 2020
7.2 pg/mL or less

Interpretive Data

Results are used to understand the pathophysiology of immune, infectious, or inflammatory disorders, or may be used for research purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Cytokine levels may demonstrate diurnal variation. For longitudinal comparison, it is recommended that cytokine levels be determined at the same time of day.

Hotline History
N/A
CPT Codes

83520 x4

Components
Component Test Code* Component Chart Name LOINC
0051536 Interleukin 1 beta, Serum 13629-1
0051537 Interleukin 6, Serum 26881-3
0051538 Interleukin 8, Serum 33211-4
0051539 Tumor Necrosis Factor - alpha, Serum 3074-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • cytokine
  • cytokines
  • IL-1 Beta
  • IL-6
  • IL-8
  • TNF Alpha
Cytokine Panel, Monokines, Serum