Epstein-Barr Virus by Quantitative PCR

0051352
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Example Reports
Detected
Not Detected
Ordering Recommendation

Quantify Epstein-Barr virus (EBV) viral load as an aid in monitoring EBV-related disease.

Mnemonic
EBV QNT
Methodology

Quantitative Polymerase Chain Reaction

Performed

Sun-Sat

Reported

2-6 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Lavender (EDTA), Pink (K2EDTA), or Serum Separator Tube (SST). Also acceptable: CSF.

Specimen Preparation

Separate serum or plasma from cells. Transfer 1 mL serum, plasma, whole blood, or CSF to a sterile container. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.
Whole Blood: Refrigerated.

Unacceptable Conditions

Heparinized specimens.

Remarks

Specimen source required.

Stability

Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year
Whole Blood: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 week

Reference Interval

Not detected

Interpretive Data

The quantitative range of this assay is 2.6-7.6 log copies/mL (390-39,000,000 copies/mL)

A negative result (less than 2.6 log copies/mL or less than 390 copies/mL) does not rule out the presence of PCR inhibitors in the patient specimen, or EBV DNA nucleic acid in concentrations below the level of detection of the assay.  Inhibition may also lead to underestimation of viral quantitation.

No international standard is currently available for calibration of this assay. Caution should be taken when interpreting results generated by different assay methodologies.

Compliance Category

Analyte Specific Reagent (ASR)

Note

The limit of quantification for this DNA assay is 2.6 log copies/mL (390 copies/mL). If the assay DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)." If the assay DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
09/08/2020
X
N/A
CPT Codes

87799

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Components
Component Test Code* Component Chart Name LOINC
0051338 EBV by Quantitative PCR, Source 31208-2
0051351 EBV by Quantitative PCR, Log copy/mL 53774-6
0051821 EBV by Quantitative PCR, Interp 5005-4
2002318 EBV by Quantitative PCR, Copy/mL 32585-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EBV
  • EBV Quant PCR
  • EBV Quant PCR Whole Blood
  • EBV quantitative
  • herpes
  • HHV-4
  • Human herpesvirus 4
  • Viral load monitoring
Epstein-Barr Virus by Quantitative PCR