Quantify Epstein-Barr virus (EBV) viral load as an aid in monitoring EBV-related disease.
Quantitative Polymerase Chain Reaction
New York DOH Approval Status
Lavender (EDTA), Pink (K2EDTA), or Serum Separator Tube (SST). Also acceptable: CSF.
Separate serum or plasma from cells. Transfer 1 mL serum, plasma, whole blood, or CSF to a sterile container. (Min: 0.5 mL)
Whole Blood: Refrigerated.
Specimen source required.
Ambient: 24 hours; Refrigerated: 5 days; Frozen: 1 year
Whole Blood: Ambient: 1 week; Refrigerated: 1 week; Frozen: 1 week
The quantitative range of this assay is 2.6-7.6 log copies/mL (390-39,000,000 copies/mL)
A negative result (less than 2.6 log copies/mL or less than 390 copies/mL) does not rule out the presence of PCR inhibitors in the patient specimen, or EBV DNA nucleic acid in concentrations below the level of detection of the assay. Inhibition may also lead to underestimation of viral quantitation.
No international standard is currently available for calibration of this assay. Caution should be taken when interpreting results generated by different assay methodologies.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Analyte Specific Reagent (ASR)
The limit of quantification for this DNA assay is 2.6 log copies/mL (390 copies/mL). If the assay DID NOT DETECT the virus, the test result will be reported as "<2.6 log copies/mL (<390 copies/mL)." If the assay DETECTED the presence of the virus but was not able to accurately quantify the number of copies, the test result will be reported as "Not Quantified."
|Component Test Code*||Component Chart Name||LOINC|
|0051338||EBV by Quantitative PCR, Source||31208-2|
|0051351||EBV by Quantitative PCR, Log copy/mL||53774-6|
|0051821||EBV by Quantitative PCR, Interp||5005-4|
|2002318||EBV by Quantitative PCR, Copy/mL||32585-2|
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