Aid in the diagnosis of non-acute (chronic phase) Chagas disease (T. cruzi).
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
New York DOH Approval Status
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Refrigerated. Also acceptable: Room temperature or frozen.
Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year
Effective November 9, 2017
|1.0 IV or less||Negative - No significant level of Trypanosoma cruzi IgG antibody detected.|
|1.1 IV||Equivocal - Questionable presence of Trypanosoma cruzi IgG antibody detected. Repeat testing in 10-14 days may be helpful.|
|1.2 IV or greater||Positive - IgG antibodies to Trypanosoma cruzi detected, which may suggest current or past infection.|
This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps). According to the CDC, at least two different serologic tests should be used to make the laboratory diagnosis of chronic Chagas Disease, as no single serologic test is sufficiently sensitive and specific.
|Component Test Code*||Component Chart Name||LOINC|
|0051076||Trypanosoma cruzi Antibody, IgG||59387-1|
- Chagas Antibody, IgG
- Tcruzi IgG Ab
- Trypanosoma cruzi Antibody, Total