Ordering Recommendation

Aid in the diagnosis of Chagas disease (T. cruzi). Order in conjunction with Parasites Smear (Giemsa Stain), Blood (0049025).

Mnemonic
CHAGAS M
Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Wed

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days of the acute specimens. Mark specimens plainly as acute or convalescent.

Storage/Transport Temperature

Refrigerated. Also acceptable: Room temperature or frozen.

Unacceptable Conditions

Plasma. Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

Less than 1:16: Negative - No significant level of Trypanosoma cruzi IgM antibody detected.
1:16 or greater: Positive - IgM antibodies to Trypanosoma cruzi detected, which may suggest current or recent infection.   

Interpretive Data

ARUP intends the use of this assay for clinical diagnosis. This assay should not be used for blood donor screening or associated re-entry protocols, or for screening Human Cell and Cellular Tissue-Based Products (HCT/Ps).

Compliance Statement A: For laboratory developed tests using a manufacturer labeled ASR as the reagent providing the specificity of the assay. Analyte Specific Reagent. This test was developed and its performance characteristics determined by ARUP Laboratories. The U. S. Food and Drug Administration has not approved or cleared this test; however, the FDA has determined that such clearance or approval is not necessary.

Note
Hotline History
N/A
CPT Codes

86753

Components
Component Test Code* Component Chart Name LOINC
0051075 Trypanosoma cruzi Antibody, IgM 13290-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Chagas Antibody, IgM
  • T cruzi IgM Ab
Trypanosoma cruzi Antibody, IgM