Ordering Recommendation

Preferred reflex test to detect Lyme disease in individuals with >4 weeks of clinical symptoms or exposure to tick. Positive/equivocal screen confirmed by immunoblot.

Mnemonic
C6 CHRON R
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunoblot

Performed

Tue

Reported

1-9 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

CSF. Contaminated, heat-inactivated, hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval
Test Number
Components
Reference Interval
0051044 Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA 0.90 LI or less:  Negative - C6 peptide antibody to B. burgdorferi not detected.
0.91 - 1.09 LI:  Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 LI or greater: Positive - C6 peptide antibody to B. burgdorferi detected.
0050255 Borrelia burgdorferi Antibody, IgG by Immunoblot Effective August 15, 2011

Negative

Interpretive Data

Refer to report

No compliance statements are in use for this test.

Note

If C6 Peptide by ELISA is 0.91 LI or greater, then IgG Immunoblot will be added. Additional charges apply.

Hotline History
N/A
CPT Codes

86618; if reflexed, add 86617

Components
Component Test Code* Component Chart Name LOINC
0051044 Borrelia burgdorferi C6 Pep Abs, ELISA 38173-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Lyme Disease
  • Lyme Disease C6 Peptide Ab Reflex Panel
  • Lyme Disease C6 Peptide Ab, ELISA Reflex to IgG WB
Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA with Reflex to IgG by Immunoblot