Ordering Recommendation

First-line serologic screening test for suspected Lyme disease. Positive or equivocal results must be confirmed by immunoblot.

Mnemonic
C6 PEP
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Tue

Reported

1-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Remove serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

CSF. Contaminated, heat-inactivated, hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year

Reference Interval

0.90 LI or less:  Negative - C6 peptide antibody to B. burgdorferi not detected.
0.91 - 1.09 LI:  Equivocal - Repeat testing in 10-14 days may be helpful.
1.10 LI or greater: Positive - C6 peptide antibody to B. burgdorferi detected.

Interpretive Data

LI - Lyme Index

No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

86618

Components
Component Test Code* Component Chart Name LOINC
0051044 Borrelia burgdorferi C6 Pep Abs, ELISA 38173-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Borrelia afzeli
  • Borrelia garinii
  • Lyme Disease
  • Lyme Disease C6 Peptide Ab, ELISA
Borrelia burgdorferi C6 Peptide Antibodies, Total by ELISA