Ordering Recommendation

Secondary testing for the evaluation of patients with recurrent and chronic infections, for whom immunoglobulin testing has already been performed.




Semi-Quantitative Multiplex Bead Assay




1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation

Serum separator tube.

Specimen Preparation

Transfer two 1 mL aliquots of serum to individual ARUP Standard Transport Tubes. (Min: 0.1 mL/aliquot)

Storage/Transport Temperature


Unacceptable Conditions



After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles).

Reference Interval

Test Number
Reference Interval
0050210 Diphtheria Antibody, IgG Antibody concentration of  > 0.1 IU/mL is usually considered protective.
0050535 Tetanus Antibody, IgG Antibody concentration of > 0.1 IU/mL is usually considered protective.
0050725 Streptococcus pneumoniae Antibodies, IgG (14 Serotypes)

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)


Hotline History


CPT Codes

86317 x16


Component Test Code* Component Chart Name LOINC
0050210 Diphtheria Antibody, IgG 13227-4
0050535 Tetanus Antibody, IgG 53935-3
0050706 Pneumo serotype 1 IgG (P13,PNX) 85954-6
0050708 Pneumo serotype 4 IgG (P7,P13,PNX) 86107-0
0050709 Pneumo serotype 5 IgG (P13,PNX) 86130-2
0050713 Pneumo serotype 6B IgG (P7,P13,PNX) 27118-9
0050715 Pneumo serotype 3 IgG (P13,PNX) 86080-9
0050716 Pneumo serotype 7F IgG (P13,PNX) 25296-5
0050717 Pneumo serotype 9N IgG (PNX) 86169-0
0050718 Pneumo serotype 14 IgG (P7,P13,PNX) 85991-8
0050719 Pneumo Serotype Interpretation 42771-6
0050721 Pneumo serotype 8 IgG (PNX) 86147-6
0050722 Pneumo serotype 9V IgG (P7,P13,PNX) 30153-1
0050723 Pneumo serotype 12F IgG (PNX) 85977-7
0050724 Pneumo serotype 18C IgG (P7,P13,PNX) 27395-3
0050726 Pneumo serotype 19F IgG (P7,P13,PNX) 86024-7
0050727 Pneumo serotype 23F IgG (P7,P13,PNX) 86064-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • Diphtheria Antitoxoid
  • Diphtheria IgG
  • Strep Pneumoniae
  • Tetanus Antitoxoid
  • Tetanus IgG
Humoral Immunity Panel II