Not a recommended panel for the diagnosis of antiphospholipid syndrome (APS). The combined IgG and IgM Phosphatidylserine test is the preferred second-line testing in seronegative APS.
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Sun, Tue, Wed, Fri, Sat
Serum separator tube.
Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.25 mL)
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
|Phosphatidylserine Antibody IgG||Less than 11 U/mL|
|Phosphatidylserine Antibody IgM||Less than 25 U/mL|
|Phosphatidylserine Antibody IgA||Less than 20 U/mL|
IgG and/or IgM antibodies to phosphatidylserine (aPS) may be associated with a positive test for anti-cardiolipin autoantibodies (aCL) and risk for obstetric antiphospholipid syndrome (APS). Strong clinical correlation is recommended in the absence of lupus anticoagulant, IgG and/or IgM cardiolipin and/or beta2 glycoprotein antibodies.
Isolated presence of IgM or IgG antibodies to aPS may have questionable clinical significance for APS and/or SLE.
If results are positive, repeat testing with two or more specimens drawn at least 12 weeks apart to demonstrate persistence of antibodies.
Results should not be used alone for diagnosis and must be interpreted in light of APS-specific clinical manifestations and/or other criteria phospholipid antibody tests.
|Component Test Code*||Component Chart Name||LOINC|
|0050906||Phosphatidylserine Antibody IgG||32032-5|
|0050907||Phosphatidylserine Antibody IgM||32033-3|
|0050908||Phosphatidylserine Antibody IgA||32031-7|
- aPS Antibodies
- aPS Antibodies IgG, IgM, IgA