Ordering Recommendation
Use for differential evaluation of patients with systemic lupus erythematosus (SLE), Sjögren syndrome, polymyositis/dermatomyositis, and/or other tissue diseases or overlapping syndromes.
Mnemonic
SSA/SSB
Methodology
Semi-Quantitative Multiplex Bead Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum separator tube.
Specimen Preparation
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Plasma or other body fluids. Contaminated, hemolyzed, or severely lipemic specimens.
Remarks
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
SSA-52 (Ro52) (ENA) Antibody, IgG | 40 AU/mL or less | |
SSB (La) (ENA) Antibody, IgG | 40 AU/mL or less | |
SSA-60 (Ro60) (ENA) Antibody, IgG | 40 AU/mL or less |
Interpretive Data
Component |
Interpretation |
---|---|
SSA-52 (Ro52) (ENA) Antibody, IgG | 29 AU/mL or Less Negative 30-40 AU/mL Equivocal 41 AU/mL or greater Positive |
SSA-60 (Ro60) (ENA) Antibody, IgG | 29 AU/mL or Less Negative 30-40 AU/mL Equivocal 41 AU/mL or greater Positive |
SSB (La) (ENA) Antibody, IgG | 29 AU/mL or less Negative 30-40 AU/mL Equivocal 41 AU/mL or greater Positive |
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
86235 x3
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050691 | SSA-52 (Ro52) (ENA) Antibody, IgG | 31625-7 |
0050692 | SSB (La) (ENA) Antibody, IgG | 29965-1 |
2012055 | SSA-60 (Ro60) (ENA) Antibody, IgG | 53019-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Anti-ENA Anti-Ribonuclear Protein
- Ro Ab
- Smith (ENA) Antibody, IgG
- SSA (Ro) (ENA) Antibody, IgG
- SSA Ro
- SSB (La) (ENA) Antibody, IgG
- SSB LA
Extractable Nuclear Antigen Antibodies (SSA 52, SSA 60, and SSB)