Ordering Recommendation

Not recommended as an initial test to evaluate for suspected celiac disease (CD). May be used to evaluate for suspected CD in individuals with positive results for tissue transglutaminase (tTG) IgA.

The preferred test to screen for CD is Celiac Disease Reflexive Cascade, Serum (3016817).

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. Severely lipemic, contaminated, or hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid freeze/thaw cycles)

Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Mon-Fri

Reported

1-5 days

Reference Interval

Less than 1:10

Interpretive Data

The endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86231

Components

Component Test Code* Component Chart Name LOINC
0050736 Endomysial Antibody, IgA Titer 27038-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Anti-Endomysial Antibodies
  • EMA
  • EMA IgA
  • Gluten-Sensitive Enteropathy Tests
Endomysial Antibody, IgA by IFA