Ordering Recommendation

• Acceptable single screening test for IgA-competent individuals with suspected celiac disease.
• Preferred screening test for individuals with suspected celiac disease is Celiac Disease Reflexive Cascade (2008114) or Tissue Transglutaminase (tTG) Antibody, IgA (0097709). (IgA testing recommended to identify IgA competence.)
• May aid in monitoring adherence to gluten-free diet in celiac disease confirmed patients.

Mnemonic
EMAR TITER
Methodology

Semi-Quantitative Indirect Fluorescent Antibody

Performed

Mon-Fri

Reported

1-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma. Severely lipemic, contaminated, or hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid freeze/thaw cycles)

Reference Interval

Less than 1:10

Interpretive Data

The endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86256

Components
Component Test Code* Component Chart Name LOINC
0050736 Endomysial Antibody, IgA Titer 27038-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Anti-Endomysial Antibodies
  • EMA
  • EMA IgA
  • Gluten-Sensitive Enteropathy Tests
Endomysial Antibody, IgA by IFA