Ordering Recommendation
Aids in the diagnosis and monitoring of patients with multiple sclerosis and other inflammatory disease of the nervous system.
Mnemonic
IGG SYN
Methodology
Quantitative Immunoturbidimetry
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
CSF AND serum separator tube. Serum specimen should be drawn within 48 hours of CSF collection.
Specimen Preparation
Centrifuge and separate CSF to remove cellular material. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL CSF AND 1 mL serum to individual ARUP Standard Transport Tubes. (Min: 0.5 mL CSF AND 0.5 mL serum)
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Grossly bloody or hemolyzed specimens.
Remarks
Stability
Ambient: Unacceptable; Refrigerated: 14 days; Frozen: 6 months (if frozen within 24 hours)
Reference Interval
Test Number |
Components |
Reference Interval |
||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Albumin, CSF | 0-35 mg/dL | |||||||||||||||
Immunoglobulin G |
|
|||||||||||||||
Immunoglobulin G CSF | 0.0-6.0 mg/dL | |||||||||||||||
Albumin, Serum | 3500-5200 mg/dL | |||||||||||||||
Albumin Index | 0.0-9.0 | |||||||||||||||
CSF IgG Synthesis Rate | Less than or equal to 8.0 mg/d | |||||||||||||||
CSF IgG/Albumin Ratio | 0.09-0.25 | |||||||||||||||
IgG Index | 0.28-0.66 |
Interpretive Data
Compliance Category
FDA
Note
Hotline History
Hotline History
Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
N/A
CPT Codes
82784 x2; 82040; 82042
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050200 | Albumin, CSF | 1746-7 |
0050350 | Immunoglobulin G | 2465-3 |
0050670 | Immunoglobulin G CSF | 2464-6 |
0050671 | Albumin, Serum | 1751-7 |
0050672 | Albumin Index | 1756-6 |
0050675 | CSF IgG Synthesis Rate | 14116-8 |
0080175 | CSF IgG/Albumin Ratio | 2470-3 |
0080180 | IgG Index | 14117-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Cerebrospinal fluid index
- CSF index IgG
- IgG, CSF Index
- Immunoglobulin G Synthesis Rate
Immunoglobulin G, CSF Index