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Herpes Simplex Virus Type 1 and/or 2 Antibodies, IgM by ELISA
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Ordering Recommendation
Not recommended for herpes simplex virus (HSV) testing; IgM lacks adequate predictive value for acute infection. If pursuing antibody testing, refer to Herpes Simplex Type 1 and Type 2 Glycoprotein G-Specific Antibodies, IgG by CIA (0051152). If acute HSV infection is suspected, molecular testing is preferred (refer to Herpes Simplex Virus by PCR (0060041)).
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST). Also acceptable: Serum from umbilical cord blood.
Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or convalescent."
Refrigerated.
Contaminated, heat-inactivated, hemolyzed, icteric, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
| 0.89 IV or less: | Not Detected. |
| 0.90-1.09 IV: | Indeterminate - Repeat testing in 10-14 days may be helpful. |
| 1.10 IV or greater: | Detected - IgM antibody to HSV detected, which may indicate a current or recent infection. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
Interpretive Data
FDA
Note
Hotline History
CPT Codes
86694
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050641 | HSV 1 and/or 2 Abs, IgM by ELISA | 41399-7 |
Aliases
- HSV
- HSV antibodies type 1 or 2
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