Ordering Recommendation
Aids in determining past or present Epstein-Barr virus (EBV) infection as well as susceptibility to future EBV infection. May be used in conjunction with EBV nuclear antigen to diagnose primary EBV infectious mononucleosis.
Mnemonic
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST).
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Refrigerated.
Contaminated, heat-inactivated, or grossly hemolyzed specimens.
Label specimens plainly as "acute" or "convalescent."
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles).
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
EBV Antibody to Viral Capsid Antigen IgG | 21.9 U/mL or less | |
EBV Antibody to Viral Capsid Antigen IgM | 43.9 U/mL or less |
Interpretive Data
Component | Interpretation |
---|---|
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG | 17.9 U/mL or less: Not Detected 18.0-21.9 U/mL: Indeterminate. Repeat testing in 10-14 days may be helpful. 22.0 U/mL or greater: Detected |
Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM | 35.9 U/mL or less: Not Detected 36.0-43.9 U/mL: Indeterminate. Repeat testing in 10-14 days may be helpful. 44.0 U/mL or greater: Detected |
FDA
Note
Hotline History
CPT Codes
86665 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050235 | EBV Antibody to Viral Capsid Antigen IgG | 7885-7 |
0050240 | EBV Antibody to Viral Capsid Antigen IgM | 7886-5 |
Aliases
- EBV Antibodies
- EBV Antibody Panel II
- EBV VCA-IgG Ab
- EBV VCA-IgM Ab
- Infectious Mononucleosis Antibody Panel
- VCA (Viral Capsid Antigen) IgG and IgM