Ordering Recommendation

Aids in determining past or present Epstein-Barr virus (EBV) infection as well as susceptibility to future EBV infection. May be used in conjunction with EBV nuclear antigen to diagnose primary EBV infectious mononucleosis.

Mnemonic
EBV PAN 2
Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Mon-Sun

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, or grossly hemolyzed specimens.

Remarks

Label specimens plainly as "acute" or "convalescent."

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles).

Reference Interval
Test Number
Components
Reference Interval
0050235 Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG Effective February 19, 2013

17.9 U/mL or less: Not Detected
18.0-21.9 U/mL:  Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
0050240 Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM Effective February 19, 2013

35.9 U/mL or less: Not Detected
36.0-43.9 U/mL: Indeterminate.   Repeat testing in 10-14 days may be helpful.
44.0 U/mL or greater: Detected

Interpretive Data



No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

86665 x2

Components
Component Test Code* Component Chart Name LOINC
0050235 EBV Antibody to Viral Capsid Antigen IgG 7885-7
0050240 EBV Antibody to Viral Capsid Antigen IgM 7886-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EBV Antibodies
  • EBV Antibody Panel II
  • EBV VCA-IgG Ab
  • EBV VCA-IgM Ab
  • Infectious Mononucleosis Antibody Panel
  • VCA (Viral Capsid Antigen) IgG and IgM
Epstein-Barr Virus Antibody Panel II