Ordering Recommendation

Aids in diagnosis of primary Epstein-Barr virus infectious mononucleosis after a suspected false-negative heterophile antibody (Monospot) test.

Mnemonic
EBV PAN
Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Mon-Sun

Reported

1-2 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transport 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, or grossly hemolyzed specimens.

Remarks

Label specimens plainly as "acute" or "convalescent."

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0050235 Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgG Effective February 19, 2013

17.9 U/mL or less: Not Detected
18.0-21.9 U/mL:  Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
0050240 Epstein-Barr Virus Antibody to Viral Capsid Antigen, IgM Effective February 19, 2013

35.9 U/mL or less: Not Detected
36.0-43.9 U/mL: Indeterminate.   Repeat testing in 10-14 days may be helpful.
44.0 U/mL or greater: Detected
0050245 Epstein-Barr Virus Antibody to Nuclear Antigen, IgG Effective February 19, 2013

17.9 U/mL or less: Not Detected
18.0-21.9 U/mL: Indeterminate.  Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
0050225 Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG Effective February 19, 2013

8.9 U/mL or less: Not Detected
9.0-10.9 U/mL: Indeterminate - Repeat testing in 10-14 days may be helpful.
11.0 U/mL or greater: Detected

Interpretive Data



No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

86665 x2; 86664; 86663

Components
Component Test Code* Component Chart Name LOINC
0050225 EBV Antibody to Early (D) Antigen IgG 50969-5
0050235 EBV Antibody to Viral Capsid Antigen IgG 7885-7
0050240 EBV Antibody to Viral Capsid Antigen IgM 7886-5
0050245 EBV Antibody to Nuclear Antigen IgG 30083-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • EA-D IgG Ab
  • EBNA-IgG Ab
  • EBV Antibodies
  • EBV Antibody Panel I
  • EBV VCA-IgG Ab
  • EBV VCA-IgM Ab
  • Infectious Mononucleosis Antibody Panel
Epstein-Barr Virus Antibody Panel I