Rubella Antibodies, IgG and IgM
Ordering Recommendation
Aid in the diagnosis of suspected rubella infection.
New York DOH Approval Status
Specimen Required
Serum separator tube.
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Refrigerated.
Plasma or urine. Contaminated, heat-inactivated, or hemolyzed specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Rubella Antibody IgM | 19.9 AU/mL or less |
Interpretive Data
Testing immediately post-exposure is of no value without a later convalescent specimen. While the presence of IgM antibodies suggests current or recent infection, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
The magnitude of the measured result is not indicative of the amount of antibody present.
Component | Reference Interval |
---|---|
Rubella Antibody, IgG | Less than 9 IU/mL: Not Detected. 9-9.9 IU/mL: Indeterminate - Repeat testing in 10-14 days may be helpful. 10 IU/mL or greater: Detected. |
Rubella Antibody, IgM | 19.9 AU/mL or less: Not Detected. 20.0 - 24.9 AU/mL: Indeterminate - Repeat testing in 10-14 days may be helpful. 25.0 AU/mL or greater: Detected - IgM antibody to rubella detected, which may indicate a current or recent infection or immunization. |
FDA
Note
Hotline History
CPT Codes
86762 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050551 | Rubella Antibody IgM | 5335-5 |
0050771 | Rubella Antibody IgG | 8014-3 |
Aliases
- Rubella Ab, IgG IgM
- Rubella Antibodies, IgG and IgM
- rubella panel
- Rubella serology