Ordering Recommendation

Aid in the diagnosis of suspected rubella infection.

Mnemonic
RUBE G/M
Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma or urine. Contaminated, heat-inactivated, or hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0050771 Rubella Antibody, IgG
Less than 9 IU/mL: Not Detected.
9-9.9 IU/mL: Indeterminate - Repeat testing in 10-14 days may be helpful.
10 IU/mL or greater: Detected.

0050551 Rubella Antibody, IgM
19.9 AU/mL or less: Not Detected.
20.0 - 24.9 AU/mL: Indeterminate - Repeat testing in 10-14 days may be helpful.
25.0 AU/mL or greater: Detected - IgM antibody to rubella detected, which may indicate a current or recent infection or immunization.

Interpretive Data

Testing immediately post-exposure is of no value without a later convalescent specimen. While the presence of IgM antibodies suggests current or recent infection, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

The magnitude of the measured result is not indicative of the amount of antibody present.

Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86762 x2

Components
Component Test Code* Component Chart Name LOINC
0050551 Rubella Antibody IgM 5335-5
0050771 Rubella Antibody IgG 8014-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Rubella Ab, IgG IgM
  • Rubella Antibodies, IgG and IgM
  • rubella panel
  • Rubella serology
Rubella Antibodies, IgG and IgM