Ordering Recommendation

May be used to confirm disease occurrence if PCR or culture is not a viable option.

Mnemonic
COX A9
Methodology

Semi-Quantitative Complement Fixation

Performed

Sun-Sat

Reported

1-3 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Less than 1:8

Interpretive Data

Single positive antibody titers of greater than 1:32 may indicate past or current infection. Seroconversion or an increase in titers between acute and convalescent sera of at least fourfold is considered strong evidence of current or recent infection.

Compliance Category

Standard

Note
Hotline History
N/A
CPT Codes

86658

Components
Component Test Code* Component Chart Name LOINC
0050503 Coxsackie A Serotype 9 Titer 9757-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • Coxsackie A Ab Panel
  • Coxsackie A Antibodies
  • Enterovirus
Coxsackie A9 Virus Antibodies by CF