Ordering Recommendation

Initial screening test for syphilis (traditional algorithm). Confirmatory test for reactive treponemal test (eg, EIA, CIA) (reverse algorithm)  Preferred test for monitoring treatment response in established syphilis. 

Mnemonic
RPRT
Methodology

Semi-Quantitative Charcoal Agglutination

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.4 mL) Avoid freezing if possible.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Plasma, CSF, or other body fluids.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval
Test Code Components Reference Interval
Rapid Plasma Reagin (RPR) RPR (+) = Reactive
RPR (-) = Nonreactive
Rapid Plasma Reagin (RPR) Titer < 1:1

Interpretive Data



Compliance Category

FDA

Note

If RPR is reactive, then a titer will be added. Additional charges apply.

Hotline History
N/A
CPT Codes

86592; if reflexed, add 86593

Components
Component Test Code* Component Chart Name LOINC
0050472 Rapid Plasma Reagin (RPR) 20507-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • RPR Titer Reflex
  • RPR with Reflex to Titer
  • Treponema pallidum with Reflex to Titer
Rapid Plasma Reagin (RPR) with Reflex to Titer