0050384
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Rickettsia typhi (Typhus Fever) Antibodies, IgG & IgM by IFA

TYPHU G/M
Example Reports
Negative
Positive

Ordering Recommendation

Confirm presence of Rickettsia typhi. Requires comparison of acute- to convalescent-phase serology.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP standard transport tube. (Min: 0.4 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Remarks

Mark specimens plainly as "acute" or "convalescent."

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Indirect Fluorescent Antibody (IFA)

Performed

Sun-Sat

Reported

1-3 days

Reference Interval

Test Number
 Components
 Reference Interval
  Typhus Fever Antibody, IgG Less than 1:64
  Typhus Fever Antibody, IgM Less than 1:64

Interpretive Data




Component
 Unit Of Measure
 Interpretation
Typhus Fever Antibody, IgG Less than 1:64
1:64-1:128
1:256 or greater		 Negative - No significant level of IgG antibody detected.
Equivocal - Questionable presence of IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
Positive - Presence of IgG antibody detected, suggestive of current or past infection.
Typhus Fever Antibody, IgM Less than 1:64
1:64 or greater		 Negative - No significant level of IgM antibody detected.
Positive - Presence of IgM antibody to detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86757 x2

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Components

Component Test Code* Component Chart Name LOINC
0050381 Typhus Fever Antibody, IgG 5324-9
0050383 Typhus Fever Antibody, IgM 5325-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Murine Typhus Antibodies
  • R. typhi antibodies
  • Typhus Fever Group Antibody, IgG and IgM, Serum
Rickettsia typhi (Typhus Fever) Antibodies, IgG & IgM by IFA