Ordering Recommendation
Confirm presence of Rickettsia typhi. Requires comparison of acute- to convalescent-phase serology.
Mnemonic
TYPHU G/M
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Sun-Sat
Reported
1-3 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum Separator Tube (SST).
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Storage/Transport Temperature
Refrigerated.
Unacceptable Conditions
Contaminated, hemolyzed, or severely lipemic specimens.
Remarks
Mark specimens plainly as "acute" or "convalescent."
Stability
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
Typhus Fever Antibody, IgG | Less than 1:64 | |
Typhus Fever Antibody, IgM | Less than 1:64 |
Interpretive Data
Component | Interpretation |
---|---|
Rickettsia typhi (Typhus Fever) Antibody, IgG by IFA | Less than 1:64 Negative - No significant level of IgG antibody detected. 1:64-1:128 Equivocal - Questionable presence of IgG antibody detected. Repeat testing in 10-14 days may be helpful. 1:256 or greater Positive - Presence of IgG antibody detected, suggestive of current or past infection |
Rickettsia typhi (Typhus Fever) Antibody, IgM by IFA | Less than 1:64 Negative - No significant level of IgM antibody detected. 1:64 or greater Positive - Presence of IgM antibody to detected, which may indicate a current or recent infection; however, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection. |
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
86757 x2
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050381 | Typhus Fever Antibody, IgG | 5324-9 |
0050383 | Typhus Fever Antibody, IgM | 5325-6 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- Murine Typhus Antibodies
- R. typhi antibodies
- Typhus Fever Group Antibody, IgG and IgM, Serum
Rickettsia typhi (Typhus Fever) Antibodies, IgG & IgM by IFA