Ordering Recommendation

Aid in the diagnosis of measles infection. Test may not be helpful in patients who have recently received an MMR vaccination.

Mnemonic

MEASLE PAN

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Semi-Quantitative Chemiluminescent Immunoassay

Performed

Mon, Wed, Fri

Reported

1-6 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Refer to individual components.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

Test Number
Components
Reference Interval
  Measles, Rubeola, Antibody IgM 0.79 AU or less

Interpretive Data




Component Interpretation
Measles (Rubeola) Antibody, IgG 13.4 AU/mL or less: Negative - No significant level of detectable measles (rubeola) IgG antibody.
13.5-16.4 AU/mL: Equivocal - Repeat testing in 10-14 days may be helpful.
16.5 AU/mL or greater: Positive - IgG antibody to measles (rubeola) detected, which may indicate a current or past exposure/immunization to measles (rubeola).
Measles (Rubeola) Antibody, IgM 0.79 AU or less: Negative - No significant level of IgM antibodies to measles (rubeola) virus detected.
0.80-1.20 AU: Equivocal - Repeat testing in 10-14 days may be helpful.
1.21 AU or greater: Positive - IgM antibodies to measles (rubeola) virus detected. Suggestive of current or recent infection or immunization. However, low levels of IgM antibodies may occasionally persist for more than 12 months post-infection or immunization.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86765 x2

Components

Component Test Code* Component Chart Name LOINC
0050380 Measles, Rubeola, Antibody IgG 7962-4
0099597 Measles, Rubeola, Antibody IgM 25421-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • rubeola antibody panel
  • rubeola IgG IgM
  • Rubeola serology
Measles (Rubeola) Antibodies, IgG and IgM