Ordering Recommendation
Detect circulating immune complexes.
Mnemonic
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Mon, Thu, Sat
Reported
2-9 days
New York DOH Approval Status
Specimen Required
Plain red or serum separator tube (SST)
Allow complete clotting of red blood cells (up to 1 hour), then separate serum from cells within 30 minutes and freeze immediately. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) If ordered in conjunction with a Circulating Immune Complex, C3 fragments, transfer TWO (2) 1 mL aliquots of serum to individual ARUP Standard Transport Tubes.
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Non-frozen specimens.
After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)
Reference Interval
Effective February 19, 2019
Less than or equal to 3.9 µg Eq/mL
Interpretive Data
Less than or equal to 3.9 µg Eq/mL is considered negative for circulating complement binding immune complexes. Circulating immune complexes may be found without any evident pathology and positive results do not necessarily implicate the immune complex in a disease process.
FDA
Note
Hotline History
Hotline History
CPT Codes
86332
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050301 | Circulating Immune Complex, C1q Binding | 27831-7 |
Aliases
- CIC
- Circulating complement binding immune complex
- Immune Complex Assay