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Epstein-Barr Virus Antibody to Nuclear Antigen, IgG
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Ordering Recommendation
Order to document past Epstein-Barr virus (EBV) exposure or, in conjunction with other serologic tests, diagnose primary EBV infectious mononucleosis.
Mnemonic
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
1-2 days
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST).
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Refrigerated.
Contaminated, heat-inactivated or grossly hemolyzed specimens.
Label specimens plainly as ''acute'' or ''convalescent.''
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Effective February 19, 2013
17.9 U/mL or less: Not Detected
18.0-21.9 U/mL: Indeterminate. Repeat testing in 10-14 days may be helpful.
22.0 U/mL or greater: Detected
Interpretive Data
FDA
Note
EBNA values obtained with different manufacturers' assay methods may not be used interchangeably. The magnitude of the reported EBNA level cannot be correlated to an endpoint titer.
Hotline History
CPT Codes
86664
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050245 | EBV Antibody to Nuclear Antigen IgG | 30083-0 |
Aliases
- EBNA Antibody
- EBNA-IgG Ab
- EBV Antibodies
- EBV Antibody to Nuclear Antigen
- EBV Nuclear Antibody
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