Ordering Recommendation

Screening test and titer for the detection of Cryptococcus species, an etiologic agent of fungal meningitis. Confirmation by culture is required. Order Fungal Culture (0060149) if culture is not performed at client site. 

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

CSF.

Specimen Preparation

Transfer 1 mL CSF to a sterile ARUP standard transport tube (ARUP supply #43115). Available online through eSupply using ARUP Connect(TM) or contact ARUP Client Services at 800-522-2787. (Min: 0.25 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions
Remarks
Stability

Ambient: 1 hour; Refrigerated: 1 week; Frozen: 1 week

Methodology

Semi-Quantitative Enzyme Immunoassay (EIA)

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Negative

Interpretive Data



Compliance Category

FDA

Note

A titer is performed on all positive specimens. Titer results are reported to the client. The College of American Pathologists (CAP) requires that Cryptococcal antigen detection testing performed on CSF specimens be confirmed by culture (CAP MIC.42005). All specimens will be tested with the assumption that a culture was performed before sending to ARUP Laboratories unless a specific request for culture is added to the test order (Fungal Culture, ARUP test code 0060149).

Hotline History

N/A

CPT Codes

87327

Components

Component Test Code* Component Chart Name LOINC
0050195 Cryptococcus Antigen CSF, EIA 29896-8
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • cryptococcal antigen
  • Cryptococcus Ag Screen, CSF
  • Cryptococcus Antigen, Spinal Fluid
  • India ink
Cryptococcus Antigen, CSF