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Cryptococcus Antigen, CSF
Ordering Recommendation
Identify Cryptococcus as an etiological agent of meningitis. CAP requires confirmation by culture for this test; order Cerebrospinal Fluid (CSF) Culture and Gram Stain (0060106).
Methodology
Semi-Quantitative Enzyme Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
Specimen Required
CSF.
Transfer 1 mL CSF to a sterile ARUP Standard Transport Tube (ARUP supply #43115). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.25 mL)
Refrigerated.
Ambient: 1 hour; Refrigerated: 1 week; Frozen: 1 week
Reference Interval
Negative
Interpretive Data
FDA
Note
A titer is performed on all positive specimens. Titer results are reported to the client. The College of American Pathologists (CAP) requires that Cryptococcal antigen detection testing performed on CSF specimens be confirmed by culture (CAP MIC.42005). When Cryptococcal antigen detection is ordered on CSF specimens by the University of Utah Hospital, Huntsman Cancer Hospital, or the VA Hospital of Salt Lake City, a CSF culture will be ordered automatically (see ARUP Test Code 0060106 for submission requirements). All other specimens will be processed with the assumption that a culture was performed before sending to ARUP unless a specific request for culture is included with the test order. Additional charges apply.
Hotline History
CPT Codes
87327
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050195 | Cryptococcus Antigen CSF, EIA | 29896-8 |
Aliases
- cryptococcal antigen
- Cryptococcus Ag Screen, CSF
- Cryptococcus Antigen, Spinal Fluid
- India ink
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