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Cryofibrinogen
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Ordering Recommendation
Aids in evaluation of patients with vasculitis, macroglobulinemia, or multiple myeloma in whom symptoms occur with exposure to cold.
Mnemonic
Methodology
Qualitative Cold Precipitation
Performed
Sun-Sat
Reported
3-5 days
New York DOH Approval Status
Specimen Required
Fasting specimen required.
Whole blood drawn in a pre-warmed (37°C) syringe. Specimen may be drawn directly into a pre-warmed lt. blue (sodium citrate) or black (sodium citrate).
Maintain whole blood at 37°C from collection to transport; do not refrigerate or freeze at any time. Immediately after blood has been obtained, transfer specimen to a pre-warmed blue (sodium citrate) or black (sodium citrate) (if not used for collection). Separate plasma from cells using a 37°C centrifuge, if possible. Transfer 3 mL plasma to an ARUP Standard Transport Tube. (Min: 1 mL)
Room temperature. Also acceptable: Refrigerated.
Serum. Heparinized plasma. Grossly hemolyzed or lipemic specimens.
Proper collection and transport of specimen is critical to the outcome of the assay. Quantities less than 3 mL may affect the sensitivity of the assay.
After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable
Reference Interval
Negative at 72 hours.
Interpretive Data
Standard
Note
Hotline History
CPT Codes
82585
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050190 | Cryofibrinogen | 29744-0 |
Aliases
- cryofibrinogen protein
- Cryofibrinogen, Qualitative, Plasma
- cryopreciptate
- Cryoprotein
- plasma cryofibrinogen
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