Ordering Recommendation

Aids in evaluation of patients with vasculitis, macroglobulinemia, or multiple myeloma in whom symptoms occur with exposure to cold.

Mnemonic
CRYO FIB
Methodology

Qualitative Cold Precipitation

Performed

Sun-Sat

Reported

3-5 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation

Fasting specimen required.

Collect

Whole blood drawn in a pre-warmed (37°C) syringe. Specimen may be drawn directly into a pre-warmed lt. blue (sodium citrate) or black (sodium citrate).

Specimen Preparation

Maintain whole blood at 37°C from collection to transport; do not refrigerate or freeze at any time. Immediately after blood has been obtained, transfer specimen to a pre-warmed blue (sodium citrate) or black (sodium citrate) (if not used for collection). Separate plasma from cells using a 37°C centrifuge, if possible. Transfer 3 mL plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature

Room temperature. Also acceptable: Refrigerated.

Unacceptable Conditions

Serum. Heparinized plasma. Grossly hemolyzed or lipemic specimens.

Remarks

Proper collection and transport of specimen is critical to the outcome of the assay. Quantities less than 3 mL may affect the sensitivity of the assay.

Stability

After separation from cells: Ambient: 1 week; Refrigerated: 1 week; Frozen: Unacceptable

Reference Interval

Negative at 72 hours.

Interpretive Data



Compliance Category

Standard

Note
Hotline History
N/A
CPT Codes

82585

Components
Component Test Code* Component Chart Name LOINC
0050190 Cryofibrinogen 29744-0
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • cryofibrinogen protein
  • Cryofibrinogen, Qualitative, Plasma
  • cryopreciptate
  • Cryoprotein
  • plasma cryofibrinogen
Cryofibrinogen