Ordering Recommendation

Not recommended. For initial establishment of diagnosis, refer to Coccidioides Antibodies Reflexive Panel (3001982).

Mnemonic
COCCI-PPT
Methodology

Qualitative Immunodiffusion

Performed

Sun-Sat

Reported

2-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Transfer 0.5 mL serum to an ARUP Standard Transport Tube (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Reference Interval

None detected.

Interpretive Data

Coccidioides infection is demonstrated by the detection of IgM antibody to the Immunodiffusion Tube Precipitin (IDTP) antigen. IgM antibody may be detected 1 to 3 weeks after the onset of primary infection and may suggest active or recent infection. IgM antibody is rarely detected 6 months after infection but may reappear with relapse and may persist in disseminated cases. IgG antibody may also be demonstrated in response to the Immunodiffusion Complement Fixation (IDCF) antigen and may represent active or past infection. Negative fungal serology does not rule out current infection.

No compliance statements are in use for this test.

Note

This test uses culture filtrates of Coccidioides immitis and includes IDCF and IDTP antigens.

Hotline History
N/A
CPT Codes

86635

Components
Component Test Code* Component Chart Name LOINC
0050183 Coccidioides immitis Abs, Precipitin 5095-5
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Aliases
  • Coccidioides Antibody (TP Antigen)
  • Coccidioides Antibody (TP Antigen), Immunodiffusion
  • Coccidioides antibody, S
  • Coccidioides Precipitin
  • Coccidioidomycosis IgG/IgM
  • San Joaquin Fever Antibody
  • San Joaquin Valley fever
  • Valley Fever antibodies, Cocci ID
Coccidioides immitis Antibodies by Immunodiffusion