Ordering Recommendation

Not recommended for general cardiovascular disease risk assessment in asymptomatic adults. May aid in CVD risk stratification in specific populations.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Serum separator tube. Also acceptable: Plasma separator tube, pink (K2EDTA), or green (lithium heparin).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature


Unacceptable Conditions

Hemolyzed specimens.


After separation from cells: Ambient: 11 days; Refrigerated: 2 months; Frozen: 1 year


Quantitative Immunoturbidimetry




Within 24 hours

Reference Interval

3.0 mg/L or less

Interpretive Data

Patients with higher hs-CRP concentrations are more likely to develop stroke, myocardial infarction, and severe peripheral vascular disease. 

CRP is a nonspecific marker of inflammation and a variety of conditions other than atherosclerosis may cause elevated concentrations. If the first result is greater than 3.0 mg/L, recommend repeating test at least 2 weeks later in a metabolically stable state, free of infection or acute illness.  The lower of the two results should be used to determine the patient's risk.

Significantly decreased CRP values may result in specimens from patients treated with carboxypenicillins.

hs-CRP results are used to assign risk as follows
Less than 1.0 mg/L
1.0-3.0 mg/L
Greater than 3.0 mg/L
Low risk
Average risk
High risk

Compliance Category



Hotline History


CPT Codes



Component Test Code* Component Chart Name LOINC
0050182 CRP, High Sensitivity 30522-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.


  • C Reactive Protein, Cardiac
  • C Reactive Protein, High Sensitivity
  • C-Reactive Prot, High Sens, Serum
  • C-Reactive Protein, Cardio
  • C-Reactive Protein, Sensitive
  • Cardio C-Reactive Protein
  • CRP Cardiac
  • CRP High Sensitivity
  • CRP, High Sensitivity
  • High Sensitivity, CRP
  • High-sensitivity CRP
  • Ultra-sensitive CRP
C-Reactive Protein, High Sensitivity