0050167
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Varicella-Zoster Virus Antibody, IgG

VZE
Example Reports
Negative
Positive

Ordering Recommendation

Provide evidence of vaccination or past infection with varicella-zoster virus.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube (SST).

Specimen Preparation

Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum an ARUP standard transport tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.

Remarks

Label specimens plainly as acute or convalescent.

Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Effective October 7, 2024

<=0.99 S/CO: Negative - No significant level of detectable varicella-zoster IgG antibody.
>=1.00 S/CO: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection.

Test Number
 Components
 Reference Interval
  Varicella-Zoster Virus Ab, IgG <=0.99

Interpretive Data

The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.

Compliance Category

FDA

Note

For CSF specimens, refer to Varicella-Zoster Virus Antibody, IgG, CSF (ARUP test code 0054444).

Hotline History

View Hotline History

 

Hotline History

Date of Change
Test Name Change
Methodology
Performance/Reported Schedule
Specimen Requirements
Reference Interval
Interpretive Data
Note
CPT Code
Component Change
Other Interface Change
New Test
Inactive
04/21/2025
X
X
10/07/2024
X
X
N/A

CPT Codes

86787

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Components

Component Test Code* Component Chart Name LOINC
0050167 Varicella-Zoster Virus Ab, IgG 5403-1
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Herpes Zoster Antibodies
  • VZV
  • VZV Antibody, IgG
  • Herpes Zoster
  • IgG, Serum
  • Varicella-zoster IgG
  • Varicella-Zoster Immune Status
  • VZ Ab, IgG
  • Varicella-Zoster Antibody
  • Varicella-Zoster Antibody Screen
  • VZ AB IgG
Varicella-Zoster Virus Antibody, IgG