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Varicella-Zoster Virus Antibody, IgG
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Ordering Recommendation
Provide evidence of vaccination or past infection with varicella-zoster virus.
Mnemonic
Methodology
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST).
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Refrigerated.
Contaminated, heat-inactivated, grossly hemolyzed, lipemic, or severely icteric specimens.
Label specimens plainly as acute or convalescent.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (Avoid repeated freeze/thaw cycles)
Reference Interval
Effective February 18, 2020
134.9 IV or less: Negative - No significant level of detectable varicella-zoster IgG antibody.
135.0-164.9 IV: Equivocal - Repeat testing in 10-14 days may be helpful.
165.0 IV or greater: Positive - IgG antibody to varicella-zoster detected, which may indicate a current or past varicella-zoster infection.
Interpretive Data
The best evidence for current infection is a significant change on two appropriately timed specimens, where both tests are done in the same laboratory at the same time.
FDA
Note
For CSF specimens, refer to Varicella-Zoster Virus Antibody, IgG, CSF (ARUP test code 0054444).
Hotline History
CPT Codes
86787
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0050167 | Varicella-Zoster Virus Ab, IgG | 5403-1 |
Aliases
- Herpes Zoster
- Herpes Zoster Antibodies
- IgG, Serum
- Varicella-Zoster Antibody
- Varicella-Zoster Antibody Screen
- Varicella-zoster IgG
- Varicella-Zoster Immune Status
- VZ AB IgG
- VZ Ab, IgG
- VZV
- VZV Antibody, IgG
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