Ordering Recommendation
Follow-up test for complement activity screening when CH50 and AH50 are low or absent and high suspicion remains for complement deficiency.
Mnemonic
Methodology
Quantitative Radial Immunodiffusion
Performed
Tue, Fri
Reported
3-8 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Allow specimen to clot for one hour at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.3 mL)
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Specimens left to clot at refrigerated temperature.
After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
Reference Interval
7-20 mg/dL
Interpretive Data
FDA
Note
Hotline History
CPT Codes
86160
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050156 | Complement Component 5 | 4505-4 |
Aliases
- C5
- C5 Antigen
- C5 Level
- complement terminal pathway
- Fifth component of complement
- Terminal Pathway - Complement