Ordering Recommendation

Follow-up test for complement activity screening when CH50 and AH50 are low or absent and high suspicion remains for complement deficiency.

Mnemonic
C5
Methodology

Quantitative Radial Immunodiffusion

Performed

Tue, Fri

Reported

3-8 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Allow specimen to clot for one hour at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.3 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Non-frozen specimens. Specimens exposed to repeated freeze/thaw cycles. Specimens left to clot at refrigerated temperature.

Remarks
Stability

After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

7-20 mg/dL

Interpretive Data



Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86160

Components
Component Test Code* Component Chart Name LOINC
0050156 Complement Component 5 4505-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • C5
  • C5 Antigen
  • C5 Level
  • complement terminal pathway
  • Fifth component of complement
  • Terminal Pathway - Complement
Complement Component 5