Ordering Recommendation

May assist in ruling out a complement deficiency.

Mnemonic
C4
Methodology

Quantitative Immunoturbidimetry

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection and freeze. Transport 0.5 mL serum. (Min: 0.3 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 8 days; Frozen: 3 months (avoid repeated freeze/thaw cycles)

Reference Interval
0-30 days: 8-30 mg/dL
1 month: 9-33 mg/dL
2 months: 9-37 mg/dL
3 months: 10-35 mg/dL
4 months: 10-49 mg/dL
5 months: 9-48 mg/dL
6 months: 12-55 mg/dL
7-8 months: 13-48 mg/dL
9-11 months: 16-51 mg/dL
1 year: 16-52 mg/dL
2-4 years: 12-47 mg/dL
5-11 years: 13-44 mg/dL
12-17 years: 14-41 mg/dL
18 years and older: 10-40 mg/dL

Interpretive Data



Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86160

Components
Component Test Code* Component Chart Name LOINC
0050155 Complement Component 4 4498-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • 4th Component of Complement, Serum
  • C4
  • C4 Complement Serum
  • C4, Serum
  • Complement C4, Serum
  • Fourth Component of Complement
Complement Component 4