Ordering Recommendation

Monitor rheumatologic disease.

Mnemonic
C3C4
Methodology

Quantitative Immunoturbidimetry

Performed

Sun-Sat

Reported

Within 24 hours

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.6 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 8 days; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)

Reference Interval
Test Number
Components
Reference Interval
0050150 Complement Component 3
0-30 days: 59-121 mg/dL     
1 month: 55-129 mg/dL                  
2 months: 61-155 mg/dL               
3 months: 67-136 mg/dL                
4 months: 65-182 mg/dL               
5 months: 67-174 mg/dL                
6 months: 77-179 mg/dL               
7-8 months: 78-173 mg/dL
9-11 months: 76-187 mg/dL
1 year: 87-181 mg/dL
2 years: 84-177 mg/dL
3-4 years: 80-178 mg/dL
5-11 years: 80-160 mg/dL
12-17 years: 82-163 mg/dL
18 years and older: 88-201 mg/dL

0050155 Complement Component 4
0-30 days: 8-30 mg/dL
1 month: 9-33 mg/dL
2 months: 9-37 mg/dL
3 months: 10-35 mg/dL
4 months: 10-49 mg/dL
5 months: 9-48 mg/dL
6 months: 12-55 mg/dL
7-8 months: 13-48 mg/dL
9-11 months: 16-51 mg/dL
1 year: 16-52 mg/dL
2-4 years: 12-47 mg/dL
5-11 years: 13-44 mg/dL
12-17 years: 14-41 mg/dL
18 years and older: 10-40 mg/dL

Interpretive Data



No compliance statements are in use for this test.

Note
Hotline History
N/A
CPT Codes

86160 x2

Components
Component Test Code* Component Chart Name LOINC
0050150 Complement Component 3 4485-9
0050155 Complement Component 4 4498-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • C3 & C4
  • C3/C4
Complement Components 3 and 4