0050149
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Complement Components 3 and 4

C3C4
Example Reports
Abnormal
Normal

Ordering Recommendation

Use to monitor rheumatologic disease.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube, Plasma separator tube, Green (Lithium heparin)

Specimen Preparation

Allow specimen to clot at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube and freeze. (Min: 0.6 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Specimens left to clot at refrigerated temperature. Specimens exposed to repeated freeze/thaw cycles.

Remarks
Stability

Ambient: 48 hours; Refrigerated: 8 days; Frozen: 2 weeks (avoid repeated freeze/thaw cycles)

Methodology

Quantitative Immunoturbidimetry

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Test Number
 Components
 Reference Interval
  Complement Component 3
Age Reference Interval (mg/dL)
0-30 days 59-121
1 month 55-129
2 months 61-155
3 months 67-136
4 months 65-182
5 months 67-174
6 months 77-179
7-8 months 78-173
9-11 months 76-187
1 year 87-181
2 year 84-177
3-4 years 80-178
5-11 years 80-160
12-17 years 82-163
18 years and older 90-180

  Complement Component 4
Age
 Reference Interval (mg/dL)
0-30 days 8-30
1 month 9-33
2 months 9-37
3 months 10-35
4 months 10-49
5 months 9-48
6 months 12-55
7-8 months 13-48
9-11 months 16-51
1 year 16-52
2-4 years 12-47
5-11 years 13-44
12-17 years 14-41
18 years and older 10-40

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86160 x2

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Components

Component Test Code* Component Chart Name LOINC
0050150 Complement Component 3 4485-9
0050155 Complement Component 4 4498-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • C3/C4
  • C3 & C4
Complement Components 3 and 4