Ordering Recommendation

Aids in diagnosis of hereditary angioedema and monitoring response to therapy.

Mnemonic
C1 INH F
Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun, Wed, Fri

Reported

1-4 days

New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect

Serum Separator Tube (SST).

Specimen Preparation

Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.1 mL)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Non-frozen specimens.

Remarks
Stability

After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks

Reference Interval

68% or greater: Normal
41-67%: Indeterminate
40% or less: Abnormal

Interpretive Data



Compliance Category

FDA

Note
Hotline History
N/A
CPT Codes

86161

Components
Component Test Code* Component Chart Name LOINC
0050141 C-1-Esterase Inhib. Functional 48494-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
  • C1 Esterase Inh,Func
  • C1 esterase inhibitor
  • C1 Inactivator
  • C1 INH functional
  • Functional Assay, Serum
  • Functional C1 Esterase
  • HAE
  • Hereditary Angioedema
C1-Esterase Inhibitor Functional