Ordering Recommendation
Aids in diagnosis of hereditary angioedema and monitoring response to therapy.
Mnemonic
C1 INH F
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Sun, Wed, Fri
Reported
1-4 days
New York DOH Approval Status
This test is New York DOH approved.
Specimen Required
Patient Preparation
Collect
Serum Separator Tube (SST).
Specimen Preparation
Separate from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube and freeze immediately. (Min: 0.1 mL)
Storage/Transport Temperature
CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.
Unacceptable Conditions
Non-frozen specimens.
Remarks
Stability
After separation from cells: Ambient: 2 hours; Refrigerated: Unacceptable; Frozen: 2 weeks
Reference Interval
Test Number |
Components |
Reference Interval |
---|---|---|
C-1-Esterase Inhib. Functional | 41% or greater |
Interpretive Data
Component |
Interpretation |
---|---|
C-1 Esterase Inhibitor Functional | 68% or greater Normal 41-67% Indeterminate 40% or less Abnormal |
Compliance Category
FDA
Note
Hotline History
N/A
CPT Codes
86161
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050141 | C-1-Esterase Inhib. Functional | 48494-9 |
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
- C1 Esterase Inh,Func
- C1 esterase inhibitor
- C1 Inactivator
- C1 INH functional
- Functional Assay, Serum
- Functional C1 Esterase
- HAE
- Hereditary Angioedema
C1-Esterase Inhibitor Functional