Ordering Recommendation

Mnemonic

C1 INH PAN

Methodology

Immunoturbidimetry/Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Quantitative Turbidimetric

Performed

Wed, Fri, Sat

Reported

1-4 days

New York DOH Approval Status

This test is New York DOH approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer three 1 mL aliquots of serum to individual ARUP Standard Transport Tubes and freeze immediately. (Min: 1.0 mL/tube)

Storage/Transport Temperature

CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions

Non-frozen specimens.

Remarks
Stability

Refer to individual components.

Reference Interval

Test Number
Components
Reference Interval
  C-1-Esterase Inhibitor 21-38 mg/dL
  C-1-Esterase Inhib. Functional 41% or greater
  Complement Component 4
Age Reference Interval (mg/dL)
0-30 days 8-30
1 month 9-33
2 months 9-37
3 months 10-35
4 months 10-49
5 months 9-48
6 months 12-55
7-8 months 13-48
9-11 months 16-51
1 year 16-52
2-4 years 12-47
5-11 years 13-44
12-17 years 14-41
18 years and older 10-40

Interpretive Data




Component Interpretation
C1-Esterase Inhibitor Functional 68% or greater     Normal
41-67%      Indeterminate
40% or less      Abnormal

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86160 x2; 86161

Components

Component Test Code* Component Chart Name LOINC
0050140 C-1-Esterase Inhibitor 4477-6
0050141 C-1-Esterase Inhib. Functional 48494-9
0050155 Complement Component 4 4498-2
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • C1
  • C1 esterase inhibitor
  • C1 esterase inhibitor, functional
  • C1 inhibitor
  • C1-inh
  • C4
  • Complement Component 4
C-1-Esterase Inhibitor Panel