Ordering Recommendation
May assist in confirming suspected Trench fever in patient with typical signs and symptoms and compatible exposure history.
Mnemonic
Methodology
Semi-Quantitative Indirect Fluorescent Antibody
Performed
Mon, Thu
Reported
1-8 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.3 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as acute or convalescent.
Refrigerated.
Contaminated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
< 1:64 Negative - No significant level of Bartonella quintana IgG antibody detected.
1:64-1:128 Equivocal - Questionable presence of Bartonella quintana IgG antibody detected. Repeat testing in 10-14 days may be helpful.
≥1:256 Positive - Presence of IgG antibody to Bartonella quintana detected, suggestive of current or past infection.
Interpretive Data
A low positive result suggests past exposure or infection, while a high positive result may indicate recent or current infection, but is inconclusive for diagnosis. Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.
This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.
Analyte Specific Reagent (ASR)
Note
Hotline History
CPT Codes
86611
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050094 | Bartonella quintana Antibody, IgG | 9360-9 |
Aliases
- B. quintana IgG
- Bartonella quintana IgG