Entamoeba histolytica (amebiasis), Antibody, IgG
Ordering Recommendation
Aid in the detection of amebic liver abscess. Test is not useful for intestinal infection.
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Refrigerated.
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Tue, Fri
Reported
1-5 days
Reference Interval
Effective February 6, 2017
8 U or less: Negative - No significant level of detectable E. histolytica IgG antibody.
9 - 11 U: Equivocal - Repeat testing in 10-14 days may be helpful.
12 U or greater: Positive - IgG antibody to E. histolytica detected, suggestive of a current or past infection.
Interpretive Data
Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.
FDA
Note
In the case of extraintestinal complications, a positive antibody can indicate amebiasis even though stool findings are negative.
Hotline History
CPT Codes
86753
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050070 | E. histolytica (amebiasis), Ab, IgG | 9522-4 |
Aliases
- Amebiasis histolytica Antibody
- E histolytica IgG Antibody
- E. histolytica Antibody
- Ova and Parasite Exam