Entamoeba histolytica (amebiasis), Antibody, IgG
Ordering Recommendation
Aid in the detection of amebic liver abscess. Test is not useful for intestinal infection.
Methodology
Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Performed
Tue, Fri
Reported
1-5 days
New York DOH Approval Status
Specimen Required
Serum separator tube.
Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."
Refrigerated.
Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval
Effective February 6, 2017
8 U or less: Negative - No significant level of detectable E. histolytica IgG antibody.
9 - 11 U: Equivocal - Repeat testing in 10-14 days may be helpful.
12 U or greater: Positive - IgG antibody to E. histolytica detected, suggestive of a current or past infection.
Interpretive Data
Seroconversion between acute and convalescent sera is considered strong evidence of recent infection. The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.
FDA
Note
In the case of extraintestinal complications, a positive antibody can indicate amebiasis even though stool findings are negative.
Hotline History
CPT Codes
86753
Components
Component Test Code* | Component Chart Name | LOINC |
---|---|---|
0050070 | E. histolytica (amebiasis), Ab, IgG | 9522-4 |
Aliases
- Amebiasis histolytica Antibody
- E histolytica IgG Antibody
- E. histolytica Antibody
- Ova and Parasite Exam