0050070
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Entamoeba histolytica (amebiasis), Antibody, IgG

AMB
Example Reports
Negative
Positive

Ordering Recommendation

Aid in the detection of amebic liver abscess. Test is not useful for intestinal infection.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, heat-inactivated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Tue, Fri

Reported

1-5 days

Reference Interval

Effective February 6, 2017

8 U or less: Negative - No significant level of detectable E. histolytica IgG antibody.
9 - 11 U: Equivocal - Repeat testing in 10-14 days may be helpful.
12 U or greater: Positive - IgG antibody to E. histolytica detected, suggestive of a current or past infection.

Interpretive Data

Seroconversion between acute and convalescent sera is considered strong evidence of recent infection.  The best evidence for infection is a significant change on two appropriately timed specimens where both tests are done in the same laboratory at the same time.

Compliance Category

FDA

Note

In the case of extraintestinal complications, a positive antibody can indicate amebiasis even though stool findings are negative.

Hotline History

N/A

CPT Codes

86753

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Components

Component Test Code* Component Chart Name LOINC
0050070 E. histolytica (amebiasis), Ab, IgG 9522-4
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Aliases

  • E histolytica IgG Antibody
  • E. histolytica Antibody
  • Ova and Parasite Exam
  • Amebiasis histolytica Antibody
Entamoeba histolytica (amebiasis), Antibody, IgG